摘要
目的 :探讨幽门螺杆菌 ( Hp)在门脉高压性胃病 ( PHG)发生、发展中的作用及临床意义。方法 :Hp检测采用快速尿素酶试验 ( rapid urease test,RUT)和 Hp- PCR检测法。结果 :肝硬化门脉高压组 Hp阳性率显著低于慢性胃炎组、消化性溃疡组 ( P<0 .0 1 ) ;Hp感染和肝功能分级无显著相关性 ;PHG慢性活动性胃炎 Hp阳性率明显高于非活动性胃炎 ( P<0 .0 1 )。结论 :Hp感染不是PHG的主要致病因素 ,但 Hp感染和
Objective: To study the effects and clinical significance of H. Pylori infection in portal hypertensive gastropathy. Methods: H. Pylori was detected by RUT and PCR. Results: H. Pylori infection rate in PHG was significantly lower than that in chronic gastritis and peptic ulcer ( P <0.01). And the rate in chronic active gastritis of PHG was significantly higher than that in non active gastritis ( P <0.01) . There were no evidences of Hp infection rate being associated with liver function grading. Conclusion: Although H.pylori infection was related with chronic active gastritis in PHG, it was not the essential pathogenesis factor in PHG.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2003年第2期185-186,共2页
Journal of Jilin University：Medicine Edition
关键词
肝硬化/病因学
门脉高压性胃病
螺杆菌
幽门/致病力
Liver cirrhosis/etiology
Portal hypertensive gastropathy
Helicobacter pylori /pathogenicity
