摘要
目的 :研制奥硝唑乳膏并对其质量进行控制。方法 :用紫外分光光度法测定奥硝唑含量 ,并进行刺激性试验和稳定性观察。结果 :含量测定平均回收率 99.4 % ,RSD =1.12 % (n =5 ) ,乳膏刺激性小、稳定性好。结论 :该乳膏制备工艺简单 ,质量可控 ,适合医院推广应用。
Objective: To investigate the preparation of ornidazole cream.Method: Ornidazole was Prepared into cream ,the content of ornidazole was determined by UV specteophotometry,the tests of irritability and the stability were performed.Result: The average recovery was 99.4%,RSD was 1.12%(n=5),The irritability was low, the cream was stable.Conclusion: The cream can be prepared easily,the quality control method for the cream is reliable and suitable for hospital preparations.
出处
《中国药师》
CAS
2004年第4期272-273,共2页
China Pharmacist
关键词
奥硝唑
乳膏
质量控制
Ornidazole
Cream
UV Specteophotometry
