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颅脑损伤与红细胞过氧化脂质水平和超氧化物歧化酶活性 被引量:4

Erythrocyte lipoperoxides levels and erythrocyte superoxide dismutase activity of the craniocerebral injury patients
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摘要 检测39例颅脑损伤患者和60例健康成人红细胞过氧化脂质(Ery-LPO)和红细胞超氧化物歧化酶活性(Ery-SODA)的结果表明,急性期患者的Ery-LPO和Ery-SODA平均水平分别显著高于和低于健康成人之值(P<0.002~0.01),颅脑损伤程度与Ery-LPO和Ery-SODA分别呈直线正相关和负相关(P<0.001~0.005),康复期患者的Ery-LPO和Ery-SODA平均水平与健康成人之值无显著差异(P>0.05);提示颅脑损伤患者体内的氧自由基反应和脂质过氧化作用在急性期时明显增强,而进入康复期后则明显趋向缓和。 Erythroeyte lipoperoxides levels and erythrocyte superoxide dismutase activity of the craniocerebral injury patients/Zhou Jun-fu, et al//Chinese Journal of Rehabilitation Medicine,1992, 7(5):202~204 The results of measuring erythrocyte lipoperoxides(Ery-LPO)levels and erythrocyte superoxide dismutase activity (Ery-SODA) of 39 craniocerebral injury patients and 60 health adults showed that the average Ery-LPO and Ery-SODA levels of the Patients in the acute stage were respectively higher and lower than those of the health adults (P<0.002~0.01). The linear correlations of the craniocerebral injury severity and Ery-LPO, Ery-SODA were respectively significant (P<0.001~0.005). The average Ery-LPO and Ery-SODA levels of the patients in the convalescence were not significantly different from those of the health adults (P>0.05). It showed that the oxygen free radicals reaction and lipoperoxidation reaction in the craniocerebral injury patients were clearly enhanced in the acute stage, but subsided in the convalescence. Author's address: No. 2 Hospital of Zhejiang Medical University, Hangzhou
出处 《中国康复医学杂志》 CAS CSCD 1992年第5期202-204,219,共4页 Chinese Journal of Rehabilitation Medicine
关键词 颅脑损伤 过氧化脂质 红细胞 Cranioccrebral injury Lipoperoxides Superoxide dismutase Erythrocyte
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  • 2闵宝珍,杨世方,于占久.血液光量子疗法对局灶性脑缺血大鼠大脑皮层局部血流量和脑水肿的影响[J].中国神经精神疾病杂志,1993,19(1):20-22. 被引量:37
  • 3白法毅,王维萍,王桂荣,高玉林,刘瑞春,刘余厚.自血光量子疗法对急性脑血管病患者48小时疗效观察[J]中国神经精神疾病杂志,1991(01).
  • 4高国栋,易声禹,莫简.脑损伤后自由基损害作用的实验研究[J]中华神经外科杂志,1988(03).
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  • 6高国栋,易声禹,莫简.脑损伤后自由基损害作用的实验研究[J]中华神经外科杂志,1988(03).
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