摘要
采用TBA法在脱氧核糖水平上研究了肌肽对Phen -CuSO4-Vc系统引起的DNA损伤的作用 ,并对其作用机理作了初步探讨。同时设甘露醇、苯甲酸钠、二甲基亚砜作对照 ,发现肌肽对DNA损伤的保护作用明显优于甘露醇、苯甲酸钠。
The effects of carnosine on DNA damage induced by ascorbate Cu-phenanthroline system was studied on deoxyribose level, using TBA reaction, and made some analysis on the mechanism carnosine protect DNA. The protect effects of Mannitol?Benzoate and Dimethylsulfoxide also been studied. It was suggested that carnosine has a higher protect effect that Mannitol?Benzoate and Dimethylsulfoxide in the right systerm.
出处
《微量元素与健康研究》
CAS
2004年第2期1-3,共3页
Studies of Trace Elements and Health
基金
河南省杰出青年科学基金 ( 0 3 1 2 0 0 1 5 0 0 )
关键词
肌肽
羟基
DNA损伤
TBA反应
Carnosine
Hydroxyl radicals
DNA damage
TBA reaction
