摘要
①目的 观察锡类贴片治疗复发性口腔溃疡的临床效果。②方法 复发性口腔溃疡病人 10 4例 ,随机分为两组 :治疗组 5 6例 ,应用锡类贴片局部治疗 ;对照组 4 8例 ,应用锡类散局部治疗。观察两组药物在病灶部位的黏附时间、病人的疼痛强度、溃疡愈合的时间及治疗有效率。③结果 治疗组用药后 3h仍有药物附着于溃疡面 ,用药 1～ 7d的疼痛强度评分低于对照组 ,差异有显著性 (t =4 .6 2～ 13.70 ,P <0 .0 1) ;治疗组溃疡面愈合时间短于对照组 ,差异有显著性 (t=2 .2 1、11.88,P <0 .0 5、0 .0 1) ;治疗组总有效率为 91.0 7% ,对照组为 5 2 .0 9% ,两组比较差异有极显著性 (χ2 =31.76 ,P <0 .0 1)。④结论 锡类贴片是一种局部治疗复发性口腔溃疡的良好药物。
ObjectiveTo investigate the therapeutic efficacy of Xilei Tiepian for recurrent oral ulcer (ROU). Methods One hundred and four patients with ROU were randomly divided into treatment group (n=56) and control group (n=48). The Xilei Tiepian was given to treatment group and Xilei-San to control one. The time of the drug adhering to the focus, pain intensity, healing of the focus and response rate were observed.ResultsFor treatment group: the drug remained on the surface of the ulcer three hours after the application of it. The pain score was lower than that of the control group one to seven days after medication, the difference was significant (t=4.62-13.70, P<0.01), the healing time of the ulcer was also shorter than that of the control group (t=2.21, 11.88, P<0.05, 0.01). The total response rate for treatment group was 91.07% and 52.09% for the control one, the difference between the two groups was extremely significant (χ2=31.76, P<0.01).ConclusionXilei-Tiepian is an effective drug for local use in the treatment of ROU. [
出处
《齐鲁医学杂志》
2004年第1期55-56,共2页
Medical Journal of Qilu
