摘要
目的 :筛选皱瘤海鞘体外抗乙肝有效部位。方法 :应用酶联免疫技术 (ELISA)测定血清中表面抗原 (HBsAg)、e抗原(HBeAg)的OD值 ,评价皱瘤海鞘不同部位抗乙肝病毒 (HBV)的活性。结果 :水溶性提取部位显示明显的抗HBsAg、HBeAg作用 ,而其他部位作用不明显。结论 :皱瘤海鞘提取物在体外具有抗乙肝病毒的作用 ,有效部位为水溶性成分。
OBJECTIVE To screen effective fractions for anti hepatitis B virus in vitro from Styela . Plicata. METHODS The OD of HBsAg?HBeAg in serum was measured by ELISA, and anti HBV effect of different fractions from Styela. Plicata was evaluated. RESULTS Anti HBV effect was demonstrated in solubility fraction, and there was no significant effect in the rest three fractions. CONCLUSIONS Extraction of Styela. Plicata has anti HBV effect ,and the effective fraction may be the water soluble components.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2004年第4期202-203,共2页
Chinese Journal of Hospital Pharmacy