摘要
目的:探讨血管性痴呆(vasculardementia,VD)患者及脑梗死患者认知功能障碍的特点,以期提高诊断水平。方法:对同期同一医院收集的30例VD患者、30例无明显认知功能障碍的脑梗死患者和30例正常人,应用简明精神状态检查量表(mini-mentalstateexamination,MMSE)、简易痴呆筛查量表(brifesereen-ingscalefordementia,BSSD)评定认知功能。结果:VD组MMSE评分(15.67±3.89)分,明显低于脑梗死对照组(27.10±1.49)分和正常对照组(29.63±0.72)分(Z=-6.684,-6.861,P<0.01),脑梗死对照组MMSE评分明显低于正常对照组(Z=-5.936,P<0.01)。VD组BSSD评分(16.90±4.32)分,明显低于脑梗死对照组(28.40±1.16)分和正常对照组(29.90±0.31)分(Z=-6.690,-6.986,P<0.01),脑梗死对照组BSSD评分明显低于正常对照组(Z=-5.705,P<0.01)。VD组与脑梗死对照组比较,物体命名和语言复述评分差异无显著性意义(P>0.05),其余各项认知功能指标评分VD组均明显低于脑梗死对照组(P<0.05或P<0.01)。VD组与正常对照组比较,物体命名评分差异无显著性意义(P>0.05),其余各项认知功能指标评分VD组均明显低于正常对照组(P<0.01)。脑梗死对照组语言复述、注意、计算和短程记忆评分明显低于正常对照组(P<0.01)。结论:VD患者以记忆减退。
AIM:To investigate the characteristics of cognitive disorder in the patients with vascular disease(VD) and cerebral infarction for promoting the diagnostic quality. METHODS:Thirty VD patients, thirty cerebral infarction patients without marked cognitive deficits, and thirty normal people,who came from the same hospital in the same period, were enrolled in the study.Mini mental state examination(MMSE) and brief screening scale for dementia(BSSD) were used to evaluate their cognitive function. RESULTS:The VD patients had lower scores of MMSE(15.67±3.89) and BSSD(16.90±4.32) as compared with the patients with cerebral infarction(27.10±1.49,28.40±1.16) and the controls(29.63±0.72, 29.90±0.31)(Z=-6.684,-6.861;Z=-6.690,-6.986,P< 0.01).The scores of MMSE and BSSD were also lower in the cerebral infarction group than in the control group(Z=-5.936,-5.705,P< 0.01).There was no significant difference between the VD patients and infarction patients in denomination and repetition(P >0.05).The VD patients had lower scores than infarction patients in the other cognitive markers(P< 0.05 or P< 0.01).There was no significant difference between the VD patients and normal controls in denomination(P >0.05).The VD patients had lower scores than the normal controls in the other markers(P< 0.01).Compared with the normal controls,the infarction patients had significant cognitive disorder in verbal comprehension,attention,calculation and short term memory(P< 0.01). CONCLUSION:Disorder in memory,attention and the functions related to language and visuospatial cognition are prominent in the VD patients.Cognitive disorder is a common complication in cerebral infarction patients.
出处
《中国临床康复》
CSCD
2004年第10期1804-1805,共2页
Chinese Journal of Clinical Rehabilitation
