期刊文献+

化疗联合放射治疗中晚期鼻咽癌疗效评价 被引量:1

Effect of Chemotherapy and Radiotherapy on Intermediate and Advanced Nasopharyngeal Carcinoma and Its Clinical Significance
下载PDF
导出
摘要 目的:评价化疗加放射治疗中晚期鼻咽癌的临床效果。方法:对84例临床Ⅲ~Ⅳ期的鼻咽癌患者分别实施单纯放射治疗(单放)组33例和化疗加放射治疗(化放)组51例行临床观察治疗前后的肿瘤大小,比较其近期的临床疗效(CR+PR)及5年生存率。结果:单放组、化放组有效率(CR+PR)分别为81.2%(17/33)、90.1%(46/51),P<0.01,5年生存率分别为42.4%(14/33)、66.6%(34/51),P<0.01。结论:化疗加放射治疗中晚期鼻咽癌可望提高临床疗效及延长患者的生存期。 Objective: To analyse the effect of the chemotherapy combined radiaotherapy on inlermediate and advanced nasopharyngeal carcinoma. Methods: Tirty-three cases of inlermediate advanced cervical cancer were treated with radiotherapy (n=33) and chemotherapy combined radiotherapy (n=51). The tumor mass was measured before and after therapy. The effect of treatments was compared based on the response rates of therapy and survival rates of 5years. Results: The objective response rates [completely remission+partial remission (CR+PR)] in radiotherapy and radiotherapy combined chemotherapy groups were 82.1% and 90.1% (P<0.01), and correspondingly, the survival rates of 5 years in both groups were 42.4% and 66.6% (P<0.01), respectively. Conclusion: Chemotherapy combined radiotherapy might be much more favor of the outcome of intermediate advanced nasopharyngeal carcinoma.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2004年第7期402-404,共3页 Chinese Journal of Clinical Oncology
关键词 化学治疗 放射治疗 中晚期鼻咽癌 Chemotherapy Radiotherapy Intermediate and advanced nasopharyngeal carcinoma Cure rate
  • 相关文献

参考文献12

二级参考文献41

  • 1管忠震.鼻咽癌化学治疗的概况[J].癌症,1989,8(2):120-121. 被引量:67
  • 2孙燕 周际昌.临床肿瘤内科手册(第3版)[M].北京:人民卫生出版社,1996.98.
  • 3谢孟新 林永刚 等.放、化综合治疗鼻咽癌--72例前瞻性随机研究[J].中国放射治疗学,1998,2(1):12-12.
  • 4[3]Forastiere AA, Neuberg D, Taylor SG, et al. Phase Ⅱ evaluation of taxol in advanced head and neck cancer: an eastern cooperative oncology group trial. J Natl Cancer Inst Monogr, 1993,15:181
  • 5[4]Tan EH, Khoo KS, Wee J, et al. Phase Ⅱtrial of a paclitaxel and carboplatin combination in Asian patients with metastatic nasopharyngeal carcinoma. Ann Oncol ,1999,10(2):235
  • 6[5]Yeo W, Leung TW, Chan AT, et al. A phase Ⅱ study of combination paclitaxel and carboplatin in advanced nasopharyngeal carcinoma. Eur J Cancer ,1998,34(13):2027
  • 7[1]Min H, Hong M, Ma J, et al. A new staging system for nasopharyngeal carcinoma in China. Int J Radiat Biol Phys, 1994,30:1037
  • 8[2]Lee AM, Poon YF, Foo W, et al. Retrospective analysis of 5 037 patients with nasopharyngeal carcinoma treated during 1976~1985: overall survival and patterns of failure. Int J Radiat Oncol Biol Phtsy,1992, 23: 261
  • 9[1]Gcara FB, Glisson BS, Sanguineti G, et al. Induction chemotherapy followed by radiotherapy versus radiotherapy alone in patients with advanced nasopharyngeal carcinuma: results of a matched cohort study[J].Cancer, 1997;79(7): 1279 ~ 1286
  • 10[2]AL - Sarraf M, LeBlanc M, Giri PG, et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase Ⅲ randomized Intergroup study 0099[J]. J Clin Oncol, 1998; 16(4): 1310~ 1317

共引文献252

同被引文献8

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部