期刊文献+

慢性肺心病血乳酸及丙酮酸含量研究 被引量:1

Serum lactate and pyruvate levels in patients with cor pulmonale
下载PDF
导出
摘要 目的 探讨肺心病患者血乳酸及丙酮酸含量及其影响因素。方法 同步测定 112例慢性肺心病患者和 74例健康献血员血清乳酸及丙酮酸含量。结果 健康献血员各年龄组血乳酸 (L)、丙酮酸 (P)及L/P比值间差异均无显著性 (P >0 .0 5 ) ,112例慢性肺心病患者中发生高乳酸血症者有 73例次 ,发生乳酸酸中毒者有 2 1例次。相关性检验分析结果表明 ,PO2 与L之间无明显相关 ,PO2 与L/P之间呈负相关 ,L与 [H+ ]之间呈正相关。结论 年龄对健康人血乳酸和丙酮酸含量无明显影响 ;血乳酸含量只能反映组织的酸中毒程度 ,不能反映组织的缺氧程度 。 Objective To investigate the serum lactateand pyruvate contents and affecting factors in 112 patients with cor pulmonale. Methods Serum lactate and pyruvate in 112 cases of cor pulmonale and 74 cases of health blood donor were measured simultaneously. Results No evident difference existed in serum lactate, pyruvate and L/P ratio among all ages of health blood donor(P>0.05). Seventy-three cases of hyperlactaemia and 21 cases of lactic acidosis were found in 112 cases of cor pulmonale. Relativity study showed that no evident relativity existed between PO 2 and L, butthat negative relativity between PO 2 and L/P ratio and positive relativity between L and . Conclusion Age has no obvious effects on serum lactate and pyruvate content. The blood lactate content can not reflectthe acidosis extent of tissues. The increased L/P ratio is of certain relationship to hypoxia.
出处 《山西医科大学学报》 CAS 2004年第2期136-137,共2页 Journal of Shanxi Medical University
关键词 慢性肺心病 血乳酸 丙酮酸 组织缺氧 影响因素 cor pulmonale lactate pyruvate
  • 相关文献

参考文献6

  • 1[1]Mizock BA. Controversies in lactic acidosis: Implication in critically ill patients[J]. JAMA, 1987, 258:497~499.
  • 2[2]Frommer JP. Lactic acidosis[J]. Med Clin North Am, 1983,67:815~818.
  • 3[3]Aduen JF, Burritt MF, Murray MJ. Blood lactate accumulation:hemodynamics and acid base status [J]. Intensive Care Med,2002, 17: 180.
  • 4[4]Lekic D, Igracki I, Djordjevic D. Maximum anaerobic effort,blood lactate concentration and acid-base disorders [J]. Pathophysiology, 1998, 5:117.
  • 5[5]oornstra JJ, Loosdrecht AA, Imhoff GW. Lactic acidosis:pathophysiology, diagnosis and treatment [J]. Nether J Medicine, 2001,59:300~302.
  • 6[6]Oya N, Togo H. Clinical condition and physiopathology of patients with cor pulmonale [J]. Nippon Naika Gakkai Zasshi,1993, 82:794~798.

同被引文献36

  • 1钱桂生.混合性酸碱失衡类型及判断的进展[J].中华内科杂志,1996,35(11):725-726. 被引量:16
  • 2慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8235
  • 3张耀频,孙培吾,麦惠成.心脏手术后混合静脉血氧饱和度与血容量心指数相关分析[J].中华胸心血管外科杂志,1997,13(1):16-18. 被引量:8
  • 4James JH, Lachette FA, Mc Carter FD, et al.Lactate is an unrrliable indicator of ti-ssue hypoxia in injury or sepsis[J]. Lancet, 1999,354 (9177) :505-508.
  • 5Hameed SM, Cohn SM.Gastric tonometry: the role of muscosal pH measurement in the mangagement of trauma[Jl.Chest, 2003, 123 (supple) : 475-481.
  • 6Walsh Ts. Recent advances in gas exchange measurement in intensive care pati-ents[J].Br J Anaesth, 2003,91:120-131.
  • 7Maynard N, Bihar D, Beale R, et al.Assessent of splanchnic oxyeation by gastric tonometry in patients with acute circulatory failure [J].JAMA, 1993,210:1202-1210.
  • 8Gomersall CD, Joynt GM, Freebairn RC, et al.Rescucitation tonometry of critica-lly ill patients based on the result of gastric : a prospective , randomized, controlled trial[J].Crit Care Med, 2000, 28 (3) : 607-614.
  • 9Knichwitz G, Aken HV, Brussel T.Gastrointestinnal Monitoring using measure-ment of in tramacosal PCO2[J].AnethAnalg, 1998,87:134.
  • 10Lebuffe G, Robin E, Vallet B.Gastric tomometry[J].Intensive Care Med, 2001,27( 1 ) :317-319.

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部