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两种医用胶原膜^(60)Co辐照改性的比较 被引量:4

A comparative study on modification of medical collagen membrane by ^(60)Co irradiation
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摘要 Membranes prepared from bovine tendon collagen and bovine skin collagen were irradiated by ()60Co.Dose rate about 22kGy/h and the doses applied were 15,25,35kGy.The degree of cross-linking and the stability of the membranes were evaluated by measuring swelling,resistance to collagenase digestion,and infra-red spectra.Based on these data,possible mechanisms of action were discussed.The results revealed that after the films were modified by ()60Co irradiation at the experimental conditions,both the degree of cross-linking and the stability of two kinds of collagen membranes were increased.Reconstituted bovine skin collagen films were more sensitive to ()60Co irradiation than bovine tendon collagen films. Membranes prepared from bovine tendon collagen and bovine skin collagen were irradiated by ()^(60)Co.Dose rate about 22kGy/h and the doses applied were 15,25,35kGy.The degree of cross-linking and the stability of the membranes were evaluated by measuring swelling,resistance to collagenase digestion,and infra-red spectra.Based on these data,possible mechanisms of action were discussed.The results revealed that after the films were modified by ()^(60)Co irradiation at the experimental conditions,both the degree of cross-linking and the stability of two kinds of collagen membranes were increased.Reconstituted bovine skin collagen films were more sensitive to ()^(60)Co irradiation than bovine tendon collagen films.
出处 《化学研究与应用》 CAS CSCD 北大核心 2004年第2期248-250,共3页 Chemical Research and Application
关键词 医用胶原膜 钴60辐照改性 交联度 稳定性 红外光谱分析 溶胀度 医用生物材料 collagen membrane ()^(60)Co irradiation degree of cross-linking stability infra-red spectra
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参考文献6

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