摘要
目的 :研究槲寄生碱对小鼠 H2 2 瘤体生长的抑制作用。方法 :以每只 0 .2 ml肿瘤细胞悬液 ,接种于小鼠右前肢腋部皮下 ,2 4 h后将小鼠随机分组 ,各组分别给不同浓度的槲寄生碱、5 - Fu、CMC- Na,均连续给药 7d,停药后 1～ 3d将小鼠拉颈处死 ,剥取瘤块称重 ,按“抑瘤率 =(1- T/ C)× 10 0 %”公式计算抑瘤率。结果 :槲寄生碱在 12 0 m g/ kg剂量时对小鼠肝癌H2 2 的抑瘤率可达 73.8%。结论
Objective:To study the inhibitive effect of mistletoe alkali to the growth of H22 tumour in mice.Methods:Experimental mice,inoculated by suspension liquid of tumor cell in axillary region near to the forelimb 0.2 ml each,had been randomly divided into 3 groups given mistletoe alkali,5-FU,CMC-Na respectively for 7 days then killed by hauling necks after auiting drugs 1-3 days,weighing the tumor,counting by the formula 'the rate of inhibiting tumor=(1-T/C)×100%'.Results:When the dosage of mistletoe alkali reaches 120mg/kg,the rate of inhibiting tumor is 73.8% to the H22 liver cancer of mice.Conclusion:Mistletoe alkali has the effective in anti-liver cancer.
出处
《实用中医药杂志》
2004年第5期227-227,共1页
Journal of Practical Traditional Chinese Medicine
关键词
槲寄生碱
肝癌
小鼠
实验研究
mistletoe alkali
liver cancer
experimental study
