摘要
综述了β-内酰胺类抗生素的药动学/药效学(PK/PD)研究进展,主要阐述了PK/PD综合参数确立的实验证据,掌握PK/PD参数有助于抗菌药物的合理应用,提高疗效,减少不良反应。
In order to promote rational use of antibiotics in clinics,reduce bacterial resistance and decrease ADRs of beta-lactam antibiotics, the recent development in pharmacokinetics/pharmacodynamics research of beta-lactam antibiotics, mainly the experimental evidences, were reviewed in this paper.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2004年第4期310-313,共4页
Chinese Journal of New Drugs
关键词
Β-内酰胺类抗生素
药动学
药效学
beta-lactams antibiotics
pharmacokinetics
pharmacodynamics