摘要
目的 探讨符合线路SPECT诊断结外淋巴瘤中的临床应用价值。方法 使用美国ADAC公司生产的VertexPlusEPICMCD/ACSPECT/PET ,对 18例术前或术后的NHL患者进行18F FDG代谢显像。对其中 9例原发和 /或继发结外NHL的显像结果进行定性和半定量分析 ,并与同期常规影像 (超声、CT)比较 ,结果经组织病理学证实。结果 符合线路SPECT 18F FDG代谢显像发现 9例结外NHL有 11个18F FDG摄取异常增高病灶 ,其对结外NHL病灶探测的敏感性、特异性和准确性分别为 85 %(11/ 13 )、10 0 %(2 / 2 )、86.7%(13 / 15 )。CT发现 6个病灶 ,其敏感性、特异性和准确性分别为 3 0 .8%(4 / 13 )、10 0 %(2 / 2 )、40 %(6/ 15 )。结论 符合线路SPECT 18F FDG代谢显像对结外淋巴瘤的诊断不失为一种有用的辅助检查方法 ,具有重要的临床价值。
Objective To investigate the clinical application value of SPECT with coincidence in the diagnosis of extranodal lymphoma. Methods Eighteen patients with NHL were performed with 18 F -FDG metabolic imaging pre- and postoperation using a Vertex Plus EPIC MCD/AC from ADAC company. The findings of 18 F -FDG metabolic images were analyzed in qualitative and semi-quantitative ways for nine of them who had an extranodal NHL located in primary and/or secondary organs determined histopathologically. 18 F -FDG images were compared with synchronous routine images such as ultrasonography and CT. Results There were 13 lesions in 9 patients with extranodal NHL in this study. SPECT with coincidence found 11 lesions of marked increasing of FDG uptake. The diagnostic sensitivity,specificity and accuracy of extranodal NHL were 85%,100% and 86.7%. CT found 6 lesions only. The sensitivity,specificity and accuracy of CT were 30.8%,100% and 40%,respectively. Conclusion 18 F -FDG metabolic imaging of SPECT with coincidence plays an important role in the diagnosis of patients with extranodal NHL,which has a clinical application significance.
出处
《中国医学影像技术》
CSCD
2004年第4期626-629,共4页
Chinese Journal of Medical Imaging Technology
