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整合素与肿瘤转移的关系研究进展 被引量：1

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摘要 肿瘤转移是一个多步骤,连续的主动过程,包括肿瘤从原发瘤生长部位脱落、侵犯周围基质进入血管以及淋巴管,在血液循环中运行并与血管内皮细胞黏附发生相互作用,然后穿出血管,在继发部位生长、刺激血管生成,形成转移瘤.肿瘤转移的起始是从侵袭上皮及内皮的基底膜开始的,基底膜的主要成分是胶原、层黏连蛋白、纤维黏连蛋白等,有利于肿瘤细胞黏附于基底膜,促进肿瘤细胞的转移.
作者 刘莉 李祖国 丁彦青 徐光炜
机构地区 武警医学院附属医院内科 第一军医大学肿瘤研究所 北京大学肿瘤医院
出处 《武警医学》 CAS 2004年第4期308-310,共3页 Medical Journal of the Chinese People's Armed Police Force
关键词 整合素 肿瘤转移 肿瘤细胞 细胞外基质 肿瘤血管生成
分类号 R730.6 [医药卫生—肿瘤]
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武警医学
2004年 第4期

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