摘要
目的 复习我国近 3年来有关突发性聋疗效的报道 ,分析对突发性聋治疗的现状。方法 检索中国生物医学文献数据库和中国期刊网医学专题全文数据库 ,以突发性聋和治疗为关键词检索 2 0 0 0～ 2 0 0 2年发表的有关突发性聋治疗的研究文章。依据国际循证医学标准 ,进行逐篇分析。结果 共检出 176篇文章 ,其中有关药物疗效的 12 6篇 ,在关于药物疗效的文章中 ,以 1996年中华医学会耳鼻咽喉科学会在上海制订的诊断和疗效标准为标准的文章 2 6篇 ,占 2 0 6 % ,设有对照试验的 89篇 ,占 70 6 % ,其中符合临床随机对照试验 (randomizedcontrolledtrials ,RCT)的 36篇约占2 8 5 % ,在纳入标准中大多数文章只提及符合中华医学会耳鼻咽喉科学会制定的 5条诊断标准 ,而对病因不明这一条未详细说明是否排除了高血压、糖尿病、高脂血症等疾病。结论 目前在我国 ,治疗突发性聋的报道很多 ,对突发性聋的诊断和疗效的评估的标准认识还不够统一 ,且有的研究者在实验设计、统计方法上还不够严谨 ,影响了突发性聋治疗研究论文的质量。
Objective To summarize and evaluate the current situation on sudden deafness in China by retrospective review of the articles appeared in Chinese journals in the past 3 years Methods The terms of sudden deafness and therapy were used to search all of the articles on the therapy of sudden deafness through the Chinese bio medicine literature data base and Chinese journal net from 2000～2002 All of the articles were analyzed according to the standards of evidence based medicine Results One hundred and seventy six articles were collected 126 were on the curative effect of medicine, of which 26(20 6%) based on the diagnosis and therapy standards settled by the otolaryngology branch of Chinese medical association in 1996,89(70 6%) were controlled clinical trials and 36(28 5%) were randomized controlled trials Most of the articles mentioned the 5 items diagnosis based and not detailed weather hypertension, diabetes and hyperlipemia were excluded Conclusions There are many articles on the therapy of sudden deafness However, the inconsistent understanding of the prognosis and evaluation and unstuck trial design limited the therapy, research and the standards of literature on sudden deafness to progress further
出处
《中华耳鼻咽喉科杂志》
CSCD
北大核心
2004年第4期241-243,共3页
Chinese Journal of Otorhinolaryngology
基金
国家自然科学资金资助 (3 0 0 0 0 189)
全军十五指令性攻关课题 (D12 0 4)
关键词
中国
突发性聋
预防
治疗
试验设计
Deafness,sudden
Therapy
Randomized controlled trials
Journal article[publication type]
