摘要
目的探讨颅内神经节细胞胶质瘤的临床特征及治疗效果。方法回顾性分析8例颅内神经节细胞胶质瘤的临床资料。结果平均发病年龄27岁,肿瘤位于大脑半球6例,脑干2例。临床表现主要为癫,影像学检查无特异性表现。显微手术全切5例,大部切除3例,放、化疗4例。随访3个月～5年,7例症状明显缓解,1例复发。结论神经节细胞胶质瘤呈相对良性过程,癫为其主要临床表现,治疗上应手术全切;对有术后残留或间变者可给予放、化疗,预后相对良好。
Objective To study the clinical characteristics and therapeutic efficacy of the patients with ganglioglioma. Methods The clinical datas of 8 patients with ganglioglioma confirmed by pathological and immunohistochemical examinations were analyzed retrospectively. Results The average age was 27 years old. Tumors were located in the cerebral hemisphere in 6 cases; the brainstem in 2. Seizure was the main symptom. The CT or MRI manifestations of gangliogomas were not specific and its diagnosis was dependent on pathological examination. The tumors were totally removed in 5 cases, subtotally in the other their cases, 4 cases were treated with radiotherapy and (or) chemotherapy. All patients were followed up for 3 months to 5 years. Seizure control was quite satisfactory: seizure free in 3 cases, good relief was obtained in 1 case. Conclusion Ganglioglioma was relatively benign. Seizure was the main symptom. Microsurgery was the treatment of choice; radiation and (or) chemotherapy should only be used in case of residual tumor and (or) malignant degeneration. The outcome of ganglioglioma was generally good.
出处
《中国微侵袭神经外科杂志》
CAS
2004年第5期205-207,共3页
Chinese Journal of Minimally Invasive Neurosurgery
