硒蛋氨酸对食管癌细胞株增生的影响被引量：4

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摘要目的:探讨硒蛋氨酸对食管癌细胞系EC9706增生的影响. 方法:通过MTT比色法、细胞生长曲线描绘研究硒蛋氨酸对食管癌细胞系EC9706增生的影响,采用流式细胞仪观察硒蛋氨酸诱导EC9706细胞凋亡的作用及对细胞周期的影响. 结果:硒蛋氨酸呈时间、剂量依赖性方式抑制EC9706细胞增生,改变细胞周期分布,增加G0/G1期细胞比例,诱导细胞凋亡. 结论:硒蛋氨酸可能通过影响细胞周期分布和诱导细胞凋亡,来抑制EC9706细胞增生.硒蛋氨酸可能是预防和治疗食管癌的一种新方法.

作者陈滋华吴清明谢国建王晓虎于皆平

机构地区郧阳医学院附属太和医院消化内科武汉大学人民医院消化内科

出处《世界华人消化杂志》 CAS 2004年第5期1215-1217,共3页 World Chinese Journal of Digestology

关键词硒蛋氨酸食管癌癌细胞株肿瘤微量元素

分类号 R735.1 [医药卫生—肿瘤]

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硒蛋氨酸对食管癌细胞株增生的影响被引量：4

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