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肝肠联合移植术后的代谢调控治疗 被引量：5

Nutritional support and metabolic intervention after combined liver and intestinal transplantation
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摘要 目的 :探讨代谢调控治疗在肝肠联合移植病人术后的应用。方法 :肝肠移植术后第 1天开始给予全肠外营养添加谷氨酰胺双肽和精氨酸 ,术后第 4天开始给予肠内营养添加谷氨酰胺和精氨酸 ,间歇应用生长激素四个疗程。根据肠功能的恢复情况 ,逐渐由肠外营养向肠内营养过渡。　结果 :移植器官功能恢复良好 ,术后 30天病人能够较好地耐受肠内营养。　结论 :应用代谢调控治疗 。 Objective: To observe the effect of nutritional support and metabolic intervention in a patient receiving combined liver and intestinal transplantation. Methods: Glycyl glutamine(Gly Gln)and arginine supplemented total parenteral nutrition(TPN) was administered since postoperative day(POD)1. Glutamine(Gln) and arginine supplemented enteral nutrition(EN) was applied since POD 4. Growth hormone(GH) was delivered intermittently since POD 4.With adaptation and tolerance, enteral feeding was progressively increased while parenteral nutrition reciprocally decreased. Results: Transplanted organs functioned well. Conclusions: Rehabilitation of the allograft function can profit from the application of nutritional support and metabolic intervention.
作者 朱亮 李宁 李幼生 李元新 李维勤 朱维铭 刘放南 倪小东 曹斌 李为苏 罗开 黎介寿
机构地区 南京大学医学院临床学院南京军区南京总医院解放军普通外科研究所
出处 《肠外与肠内营养》 CAS 2004年第3期143-146,共4页 Parenteral & Enteral Nutrition
基金 军区"十五"医学科研基金重点课题资助项目 (批准号 :0 2Z0 0 1)
关键词 肝肠联合移植术 代谢调控 精氨酸 营养支持 Combined liver and intestinal transplantation Nutritional support Metabolic intervention
分类号 R617 [医药卫生—外科学]
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参考文献11

  • 1Hammarqvist F, Sandgren A, Andersson K et al. Growth hormone together with glutaminecontaining total parenteral nutrition maintains muscle glutamine levels and results in a less negative nitrogen balance after surgical trauma [J]. Surgery, 2001,129(5) :57
  • 2Berman RS, Harrison LE, Pearlstone DB et al. Growth hormone,alone and in combination with insulin, increases whole body and skeletal muscle protein kinetics in cancer patients after surgery [J]. Ann Surgery,1999,229(1):1-10.
  • 3Li YS, Li JS, Li N et al. Glycyl-glutamine-enriched long-term total parenteral nutrition attenuates bacterial translocation following small bowel transplantation in the pig[J]. J Surg Res, 1999,82(1):106-111.
  • 4Gondolesi G, Fishbein T, Chehade M et al. Serum citrulline is a potential marker for rejection of intestinal allografts [ J ]. Transplantation Proc, 2002,34(3) :918-920.
  • 5RothE, ValentiniL, SemsrothM et al. Resistance of nitrogen metabolism to growth hormone treatment in the early phase after injury patients with multiple injuries [J]. J Trauma, 1995,38 (1):136-141.
  • 6Shaw JH, Koea JB. Metabolic basis for the management of the septic surgical patient [ J ]. World J Surg, 1993,17 ( 2 ): 154-164.
  • 7Cao Y, Feng Z, Hoos A et al. Glutamine enhances gut glutathione production[J]. JPEN,1998,22(4) :224-227.
  • 8Rhoads JM, Argenzio RA, Chen W et al. L-Glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases[J]. Am J Physiol, 1997,272 (5): G943-953.
  • 9Harry T, Kevin O, Mark R et al. Glutamine deprivation induces apoptosis in intestinal epithelial cells [J]. Surgery, 1998,124(2): 152-159.
  • 10李幼生.器官移植病人的营养支持[J].肠外与肠内营养,2003,10(2):110-113. 被引量：24

二级参考文献15

  • 1[1]Stephenson JrGR, Moretti EW,Hoalem EI, et al. Malnutrition in liver transplantation patients:Pro-operative subjective global assessment(SGA) is predictive of outcome following liver transplantation[J].Transplantation,2001,72:666-670.
  • 2[2]Pikul J, Sharpe MD,Lowndes R, et al. Degree of preoperative malnutrition is predictive of postoperative morbidity and mortality in liver transplant recipients[J]. Transplantation, 1994,57:469.
  • 3[3]Hasse JM. Nutrition assessment and support of organ transplant recipients[J].JPEN, 2001,25:120-131.
  • 4[4]Baron P, Waymack JP. A review of nutrition support for tansplant patients[J]. NCP,1993,8:12-18.
  • 5[5]Becker BN, Becker YT, Heisey DM, et al. The importance of hypoalbuminemia I kidney-pancreases transplant recipients[J]. Transplantation, 1999,68:72-75.
  • 6[6]Harison J, Mckiernan J, Neuberger JM. A prospective study on the effect of recipient nutrition status on outcome in liver transplantation[J]. Transpl Int, 1997,10:369-374.
  • 7[7]Madill J, Gutierrez C, Grossman, et al. Nutrition assessment of the lung transplant patient:body mass index as a predictor of 90-day mortality following transplantation[J]. J Heart Lung transplant,2001,20:288-296.
  • 8[8]Ploch W,Pezawas L, Attemiou O, et al.Nutritional ststus, ICU during and ICU mortality in lung transplant recipients[J]. Intensive Care Med,1996,22:1179-1185.
  • 9[9]Snell G, Bennets K, Bartolo J, et al. Body mass index as a predictor of survival in adults with fibrosis referred for lung transplantation[J]. J Heart Lung transplant,1998,17:1097-1103.
  • 10[10]Lenssen P, Bruemmer B, Aker SN, et al. Nutrition support in hematopoietic cell transplantation[J]. JPEN, 2001,25:219-228.

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二级引证文献21

肠外与肠内营养
2004年 第3期

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