摘要
目的 探讨浅表性脂肪瘤样痣的临床病理特征、鉴别诊断。方法 分析 9例浅表性脂肪瘤样痣临床资料、组织学特征 ,对其中 6例进行特殊染色并结合文献进行讨论。结果 本组男 5例、女 4例 ,发病年龄 1～ 4 2岁。临床上 ,7例为多发 (经典 )型 ,2例为局限型。皮损分布于臀部、尾骶部、大腿后上方、头部和窝 ,呈群集状丘疹和结节。病理特征为在真皮胶原组织内见成熟无包膜的脂肪细胞团 ,特殊染色示胶原纤维增厚、弹力纤维减少。结论 浅表性脂肪瘤样痣的诊断依赖临床病理的特征 ,在组织形态上浅表性脂肪瘤样痣应与Goltz综合征。
Purpose To study the clinicopathological features, differential diagnosis of nevus lipomatosus superficalis. Methods Nine cases of nevus lipomatosus superficalis were analyzed by means of clinical data and histopathologic features. Histochemical staining were performed on paraffin-embedded tissue in six cases and the literatures were reviewed. Results There were five males and four females, with age ranged 1～42 years. Seven cases were multicentric and two cases were local. The lesions were clustered group of soft, which involved buttock,upper thigh, scalp and knee. Histopathological, groups and strands of fat cells were found embedded among the collagen bundles of the dermis. Thickend collagen bundles were ascertained in sections stained with Massons trichrome. The Verhoeff-VanGieson stain showed a marked reduction in the amount and caliber of elastic fibers in the dermis. Conclusions Making diagnosis of nevus lipomatosus superficialis should depend on its typical clinicopathological characteristics. Base on the histological features, it is to distinguish nevus lipomatosus superficialis from Goltz syndrome,connective tissue nevus.
出处
《临床与实验病理学杂志》
CAS
CSCD
2004年第2期157-160,共4页
Chinese Journal of Clinical and Experimental Pathology
