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MUC1在卵巢肿瘤组织的表达及其临床意义

Expression of MUC1 in ovary tumors and its clinical significance
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摘要 目的 :监测 MUC1在卵巢肿瘤组织中的表达 ,探讨其对于卵巢肿瘤诊断及治疗的意义。方法 :采用免疫组织化学ABC方法 ,用 CA12 5抗体和从小鼠腹水中提取的 MUC1抗体对 2 0例卵巢癌、12例交界性卵巢瘤和 12例卵巢良性肿瘤组织进行检测。结果 :两种抗体的检测结果与病理诊断基本相符 ,良恶性表达存在显著性差异 ,阳性程度与临床分期及转移密切相关。结论 :MUC1在卵巢癌快速诊断及治疗监测中有重要意义。 Objective:To measure the expression of MUC1 in the ovary tumors and to investigate the clinical significance. Methods: The tissues were strained with monoclonal mouse anti-CA125 antibody or anti-MUC1 antibody by immunohistochemistry. Results:The results were the same with the pathological diagnosis. The positive extent is related to the clinical phase and transferation . Conclusion: MUC1 may play an important role in the ovary tumor fast diagnosis and treatment treatment supervision.
出处 《中国妇幼保健》 CAS 2004年第4期38-39,共2页 Maternal and Child Health Care of China
关键词 MUC1 卵巢肿瘤 诊断 治疗 免疫组织化学 MUC1 Ovary cancer Immunohistochemistry
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参考文献6

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