摘要
目的 :监测 MUC1在卵巢肿瘤组织中的表达 ,探讨其对于卵巢肿瘤诊断及治疗的意义。方法 :采用免疫组织化学ABC方法 ,用 CA12 5抗体和从小鼠腹水中提取的 MUC1抗体对 2 0例卵巢癌、12例交界性卵巢瘤和 12例卵巢良性肿瘤组织进行检测。结果 :两种抗体的检测结果与病理诊断基本相符 ,良恶性表达存在显著性差异 ,阳性程度与临床分期及转移密切相关。结论 :MUC1在卵巢癌快速诊断及治疗监测中有重要意义。
Objective:To measure the expression of MUC1 in the ovary tumors and to investigate the clinical significance. Methods: The tissues were strained with monoclonal mouse anti-CA125 antibody or anti-MUC1 antibody by immunohistochemistry. Results:The results were the same with the pathological diagnosis. The positive extent is related to the clinical phase and transferation . Conclusion: MUC1 may play an important role in the ovary tumor fast diagnosis and treatment treatment supervision.
出处
《中国妇幼保健》
CAS
2004年第4期38-39,共2页
Maternal and Child Health Care of China