摘要
目的探讨皮层动脉脑梗死(CACI)与穿支动脉脑梗死(PACI)病人血脂(TC、TG及apoA-I、apoB)、血糖、血压的关系及对预后的影响。方法测52例CACI、86例PACI及对照组39例,TC、TG、apoA-I、apoB、血糖的含量。结果CACI病人TC水平显著高于PACI病人及对照组(P<0.05);CACI病人TG水平显著高于对照组(P<0.05),而与PACI病人无差异性(P<0.05);CACI病人apoA-I水平显著低于PACI病人及对照组(P<0.05～0.001);PACI病人及CACI病人apoB水平显著高于对照组(P<0.01);CACI病人及PACI病人血糖水平显著高于对照组(P<0.001);而PACI病人血糖水平亦显著高于CACI病人(P<0.001)。CACI和PACI病人恶化组TC、TG、血糖水平显著高于好转组(P<0.001)。结论TC水平高和TG水平高是CACI病人的危险因素。apoA-I水平低及apoB水平高对CACI危险较PACI大,而高血压与PACI有关。CACI和PACI病人早期TC、TG、血糖水平升高对预后影响亦同样重要。
Objective To explore the correlation of blood lipid (TC, TG, apoA I and apoB), blood glucose and blood pressure in CACI and PACI patients, and the effects on their prognosis. Methods To detect the levels of blood sugar, TC, TG, apoA I and apoB of 52 CACI patients, 86 PACI patients and 39 normal individual. Results The TC level of CACI patients is significantly higher than that of PACI patients and the control group(P< 0.05). The TG level of CACI patients is not significantly different from PACI patients, but significantly higher than that of the control group(P< 0.05). The apoA I level of CACI patients is significantly lower than that of PACI patients and the control group(P< 0.05). The apoB level of CACI patients and PACI patients are significantly higher thanthat of the control group(P< 0.01). The blood sugar of CACI patients and PACI patients are significantly higher than that of the control group(P< 0.001),and the blood sugar of PACI patients is obviously higher than that of CACI patients(P< 0.001). The TC, TG and blood sugar levels of CACI patients and PACI patients with deteriorating condition are significantly higher than that in the patients with improving condition(P< 0.001). Conclusions High TC level and TG level are risk factors of CACI patients. Low apoA I level and high apoB are dangerous to CACI patients than to PACI patients. And high blood pressure is related to PACI patients. Increasing level of TC, TG and blood sugar in the early stage of CACI and PACI patients are also important to the prognosis of these patients.
出处
《热带医学杂志》
CAS
2004年第2期153-155,共3页
Journal of Tropical Medicine
