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左氧氟沙星治疗肺结核78例临床观察 被引量:1

Clinical effects of Levofloxacin on 78 Lung Tuberculosis
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摘要 目的 :观察左氧氟沙星治疗肺结核的近期疗效。方法 :将 78例初治肺结核病人随机分为治疗组 4 0例 ,对照组 38例 ,分别用以下方案 2SHRZV/ 4HRV、2SHRZ/ 4HR化疗 ,观察两组痰菌转阴率、病灶吸收率、症状改善率、药物不良反应。结果 :痰菌转阴率治疗组在第 2个月、6个月末分别是 75 %、95 % ,对照组分别是 5 2 .6 %、73.7% ;病变吸收率 6个月末治疗组是 92 .5 % ,对照组是 6 8.4 % ;症状改善率在治疗组第 2个月、6个月末分别是 5 5 %、90 % ,对照组分别是 2 6 .3%、6 8.4 % ;药物不良反应发生率治疗组、对照组分别是 37.5 %、34.2 %。结论 :左氧氟沙星抗结核作用疗效显著。 Objective: To observe the therapeutic effects of Levofloxacin on the lung tuberculosis.Method: The 78 patients with lung TB were designed in the test group (40 cases) in which the chemical therapy with 2SHRZV/4HRV was performed and the control group (38 cases) in which the 2SHRZ/4HR way was given, and the changes of symptoms and signs and the adverse reaction of the drug were recorded. Results: No bacillus cases in the sputum examination were up to 75% and 95% after 2 and 6 months treatment respectively in the test group; and the 52.6% and 73.7% was in the control group respectively. The absorption rate after 6 months was 92.5% and 68.4% in the test and control group respectively. 37.5% and 34.2% cases had the adverse reaction in the test and the control group respectively. Conclusion: There is a better therapeutic effect of levofloxacin on the lung tuberculosis.
作者 张健
出处 《青海医药杂志》 2004年第4期7-8,共2页 Qinghai Medical Journal
关键词 左氧氟沙星 肺结核 不良反应 耐药菌株 Tuberculosis Lung Levofloxacin Therapy
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