摘要
目的 观察冬凌草甲素体外诱导人结肠癌HCT8细胞凋亡的作用。方法 利用光镜及流式细胞仪观察不同浓度冬凌草甲素诱导结肠癌HCT8细胞凋亡的作用。结果 冬凌草甲素可诱导HCT8细胞凋亡 ,且凋亡率随着浓度的增加而增加。结论 冬凌草甲素对HCT8细胞株具有体外抗肿瘤作用 。
Objective To study the apoptosis of HCT8 cell induced by Oridonin. Methods Apoptosis and morphology variations were investigated by microscopic inspection and flow cytometry(FCM). Results Oridonin can induce HCT8 cell apoptosis. Conclusion Oridonin can effectively inhibit the growth and proliferation of HCT8 cells. This antitumor mechanism is associated with apoptosis induced by Oridonin.
出处
《河南肿瘤学杂志》
2004年第3期167-168,共2页
Henan Journal of Oncology
