摘要
应用国产安吖啶对11例急性白血病进行诱导缓解化疗,初治6例,复治5例。4例达完全缓解(CR),CR率为36.4％。其中初治者为33.3％(2/6),复治者为40％(2/5)。总有效率45.5％。该药的剂量限制性毒性反应为骨髓抑制,部分病例有肝功能损害。
Eleven patients with acute leukemia received remission induction chemotherapy with amsacrine (m-AMSA). Six patients were previously untreated, 2 were in relapse, and 3 were refractory. Four pati-ents (36.4%) reached complete remission (CR). Total response rate is 45.5%. Subset analysis showedthe following CR rates: previously untreated 33.3%, relapsed and primary refractory 40%. The dose-limiting toxicity of m-AMSA is myelosuppression. Another side effect is impairment of hepatic func-tion.
出处
《北京医科大学学报》
CSCD
1993年第5期315-317,共3页
Journal of Peking University(Health Sciences)
关键词
安吖啶
白血病
缓解率
m-AMSA
Acute leukemia
Remission rate
