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小剂量消炎痛治疗羊水过多临床观察 被引量:2

Clinical observation of small dose indomethacin to treat polyhydramnios
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摘要 目的 :探讨小剂量消炎痛治疗羊水过多的临床疗效。方法 :选择 2 0例诊断为慢性羊过多的病人 ,随机分为两组 :消炎痛组 ,服用消炎 2 5mg ,每 8hl次 ;对照组服用一般利尿剂 ,用药前后B超测量羊水平段 ,计算羊水指数 ,观察疗效及随访妊娠结局。结果 :消炎痛组有效率为 10 0 % ,用药 2d后症状即减轻 ,羊水减少 ,对照组有效率为 4 .5 % ,两组间差异显著 ,妊娠结局消炎痛组优于对照组。结论 :小剂量消炎治疗羊水过多 ,简便易行 ,无任何副作用 ,对母婴安全 ,方便 ,疗效可靠。 Objective: To study the effects of small dose indomethacin to treat polyhydramnios. Methods: Random selection of 42 patients with polyhydramnios into two groups: indomethacin group:20 patients,indomethacin 25mg,q8h,p.o;control group:22 patients: Hydrochlorothiazidum 25mg q8h p.o. During therapy, ultrasound measure ments of amniotic fluid pocket,and aminiotic fluid index to assess the efficacy of drugs. Results: Effective rate was 100% in indomethacin group,amintotic fluid volume progressive decrease was noted in 2days . Effective rate was 4.5% in control group . Pregnancy prognosis in indomethacin group was better than that in the control group. Conclusion: Small dose indomethacin therapy in the treatment of polyhydramnios was simple, no side effects and effective method were found.
出处 《河北医学》 CAS 2004年第5期408-410,共3页 Hebei Medicine
关键词 消炎痛 羊水过多 妊娠结局 Indomethacin Polyhydramnios Pregnant prognosis
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  • 1徐方,刘维靖,杨宁,周嘉莹,孙凤鸣.消炎痛栓治疗羊水过多的探讨[J].实用妇产科杂志,1998,14(4):201-202. 被引量:8
  • 2Hill LM, Breckle R, Thomas ML, et al. polyhydramnios: ultrasonically detected prevalence and neonatal outcome[J]. Obstet Gynecol,1987,69A:21.
  • 3Moise Kj . Indomethacin therapy in the treatment of symptomatic polyhydramnios[J]. Clinical obstet Gynecol,1991,34:310.
  • 4Mamopoulos M,Assimakopoulos E,Reece EA, et al. Matermal indomethacin therapy in the treatment of polyhydramnios[J]. AM J obstet Gynecol,1990,162:1225.
  • 5Carmona F, Martinez RS, Mortera C,et al. Efficacy and safety of indomethacin therapy for polyhydramnios[J]. Eur obstet Gyncol Reprod Biol,1993,50:175.

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