2Hoven R. A multi-centre observational study on the efficacy of dicural palatabs(difloxacin) for the treatment of canine cystitis[J].Journal of Veterinary Pharmacology &Therapeutics, 1997,20(suppl1):181～218.
3Timothy W J, Olchowy D V M phD.Efficacy of difloxacin in calves experimentally infected with Mannheimia haemolytica[J].American Journal of Veterinary Research, 2000,61(6):710～713.
9Frazier D L,Thompson I,et al. Comparison of fluoroquinolone pharmacokinetic parameters after creatment with marbofloxacin,enrofloxacin,and difloxacin in dogs [J]. Journal of VeterinarPharmacology & Therapeutics, 2003,23(5):293～302.
10Heinen E.Comparative pharmacokinetics of enrofloxacin and difloxacin as w ell as their main metabolites in dogs[J].Compendium on Continuing Education for the Practicing Veterinarian, 1999,(suppl 21),12～18.
9Granneman G R, Snyder K M, Shu V S. Difloxacin metabolism and pharmaeokineties in humans after single oral doses. Antimicrobial Agents and Chemotherapeutics, 1986,30 (3) :689 - 693.
10Garcia M A, Solans C, Aramayona J J, et al. Simultaneous determination of difloxacln and its primary metabolite sarafloxacin in rabbit plasma. Chromatographia, 2000,51 : 487 490.
