摘要
目的 对云南玉溪地区部分农村自然人群进行幽门螺杆菌感染的流行病学调查,开展Helicobacter pylori及其相关疾病知识的健康教育,为进行大规模人群防治打下基础。方法 于2000年11月～2001年8月采用多阶段抽样方法选取云南玉溪地区小石桥乡响水村和洛河乡把者岱村自然人群,采用13-UBT检测量H.pylori现症感染率并结合问卷调查H.pylori流行情况。根据调查得出的影响当地H.pylori感染流行因素,采取多种形式进行H.pylori相关知识健康教育,同时培养一批当地健康教育骨干,并对健康教育效果进行评价。结果①有379个对象纳入研究,问卷调查的回收率及随访率为100％。②用13C-UBT测得的H.pylori总感染率为55,94％(212/379)。③经单因素分析筛选出饮用水源、饮水习惯、吃腌莱、饮酒、饲养家禽(畜)、吃烟熏物油炸物、吸烟、经济状况、上腹部疼痛不适症状等9个与H.pylori有关的流行因素。经多因素非条件Logistic回归分析,最后筛选出饮用水源、饮水习惯、吃生大蒜、饮酒、饲养家禽(畜)和上腹胀痫不适症状等6个与H.pylori相关的重要流行因素。④开展健康教育后H.pylori基本知识的知晓率(56.1％)明显高于健康教育前的0(P<0.001);H.pylori相关疾病知识的知晓率(62.1％)明显高于健康教育前的0(P<0.001)
Objective To conduct a epidemilogical survey of Helicoacter pylori (H. pylori) infection in the countryside, Yuxi, Yunnan, and then cany out healthy knowledge education about H. pylori related diseases. Methods From November 2000 to August 2001,subjects in Xiang Shui and BaZhedai village,the rural area in Yuxi,Yunnan,were selected by multistage sampling,The current infection rate of H. pylori and epidemic factors were surveyed by questionnaire and 13C-UBT. According to the local epidemic factors, we carried out health education by multiple forms and trained a batch of local healthy educational staff, and evaluated its result. Results ①A total of 379 subjects were enrolled in this trial, all of them have been given in the questionnaires. ②The total H. polori infection rate was 55.94% .③Nine epidemic factors as follows were screening out by single factor analysis: water source, habituation of drinking water, salted vegetable,liquor, domestic fowl/livestock, food fried in oil or bloated in smoke,smoking,economic status,upper abdomen ache or malaise and so on. However,by multiple factors Logistic regression analysis, water source,habituation of drinking water,fresh garlic,liquor,domestic fowl/livestock,upper abdomen ache or malaise were the important epidemic factors associated with H. pylori. ④ After health education, the understanding rate about H, pylori is statistically significant compared with that of no health education (56.1 % vs 0% , P < 0.001 ) ;about the H. pylori-related diseases is 62.1 % vs 0% ( P < 0.001) ;and about the knowledge of protection and prevention from upper gestrointestinal diseases is 68.1 % vs 9.2% ( P < 0.001) . Conclusion ①In the rural area of Yuxi, the H. pylori infecton rate by 13C-UBT was 55.94% , which was a high incidence region. ② Poultry, livestock and water ware important mediam for HP infection in this area, which supported the viewpoint that H. pylori could be transmited by animal or fecal-oral route. Water source,habituation of drinking water,eating fresh garlic,alcohol consumption,Upper abdomen ache or malaise,etc were important epidemic factors. Among them, eating fresh garlic usually was a protective factor. ③ Performing health education about H. pylori in countryside was indispensable and effective for preventing and treating H. pylori infection.
出处
《胃肠病学和肝病学杂志》
CAS
2004年第3期258-262,共5页
Chinese Journal of Gastroenterology and Hepatology
基金
云南省卫生厅自然科学基金资助项目(编号:99M010)
