摘要
目的:研究2型糖尿病(T2DM)患者尿酸与颈动脉内膜中层厚度的相关性。方法:回顾性分析2018年1月至2021年12月入住海南医学院第二附属医院内分泌科的300例T2DM患者病历资料,均符合糖尿病诊断标准,按尿酸水平将患者分4组(~480 μmol/L)。比较4组的血尿酸水平与颈动脉内膜中层厚度的差异。结果:1) 本研究纳入300例2型糖尿病患者,随着尿酸水平的增高,CIMT、男性比例、病程、空胰岛素、空C肽、甘油三酯、尿素氮、肌酐、微量白蛋白、微量白蛋白/肌酐呈增高趋势(p 57.5岁,同时肌酐 > 66.5 μmol/L及血清尿酸 > 367.5 mmol/L,可作为预测CIMT的条件。
Objective: To study the correlation between uric acid and carotid intima-media thickness in pa-tients with type 2 diabetes mellitus (T2DM). Methods: The medical records of 300 T2DM patients admitted to the Department of Endocrinology of the Second Affiliated Hospital of Hainan Medical University from January 2018 to December 2021 were retrospectively analyzed. All patients met the diagnostic criteria for diabetes and were divided into four groups according to the level of uric acid (~480 μmol/L). Results: 1) 300 patients with type 2 diabetes were included in this study. With the increase of uric acid level, CIMT, male ra-tio, course of disease, empty insulin, empty peptide, triglyceride, urea nitrogen, microalbumin, mi-croalbumin/muscle show an increasing trend (p 57.5 years, creatinine > 66.5 μmol/L and serum uric acid > 367.5 mmol/L could be used as conditions to predict CIMT.
出处
《临床医学进展》
2023年第1期919-927,共9页
Advances in Clinical Medicine
