摘要
成功开通责任血管能及时改善急性脑梗死患者的临床结局,但约有半数人群难以恢复日常生活能力,这种现象称为无效再通。无效再通的流行病学、潜在病理生理机制、影响因素及管理措施因此受到广泛关注。本文讨论了无效再通的发病率及定义,从无复流、早期再闭塞、侧支循环不良等方面分析其可能的病理生理机制,概述了目前已知的经典危险因素对无效再通的影响,旨在筛选出那些能够通过血管内治疗真正获益的人群,并为其提供有效的干预线索,以期改善患者的长期预后。
Successfully opening the responsible blood vessel promptly improves the outcome for patients with acute ischemic stroke. However, roughly half of the population struggles to regain daily life abilities, referred to as futile recanalization. There is widespread attention on understanding the epidemiol-ogy, root causes, factors influencing this issue, and effective management strategies. This article ex-plores the occurrence and meaning of futile recanalization. We look into the potential reasons be-hind it, including issues like no blood flow, early reocclusion and poor collateral circulation, and outlines the influence of the classical risk factors known to influence ineffective recanalization, with the aim of screening those who can truly benefit from endovascular therapy and providing them with effective leads for intervention, with a view to improving the long-term prognosis of patients.
出处
《临床医学进展》
2024年第1期1412-1419,共8页
Advances in Clinical Medicine
