摘要
Chemerin是一种由脂肪细胞分泌的脂肪因子,在白色脂肪组织中高表达,以自分泌/旁分泌的方式发挥生物学作用,与肥胖、胰岛素抵抗和代谢综合征有关。近年来,Chemerin因其在不同器官和系统,如代谢、炎症和癌症等中发生控制中的多重作用而引起了特别的关注。因此,积极探索Chemerin在高血压、糖脂代谢及肿瘤等相关疾病中的作用有助于临床疾病的早期诊断,为治疗相关疾病提供新方向。
Chemerin, a adipokine secreted by adipocytes, is highly expressed in white adipose tissue and exerts its biological effects through autocrine/paracrine mechanisms. It is associated with obesity, insulin resistance, and metabolic syndrome. In recent years, Chemerin has gained particular attention due to its multiple roles in various organs and systems, such as metabolism, inflammation, and cancer control. Therefore, actively exploring the role of Chemerin in related diseases such as hypertension, glucose and lipid metabolism, and tumors can contribute to the early diagnosis of clinical diseases and provide new directions for the treatment of related diseases.
出处
《临床医学进展》
2024年第4期2647-2655,共9页
Advances in Clinical Medicine
