摘要
酶是一种具有催化功能的蛋白质,研究酶蛋白质中的二级结构对研究酶的结构及功能有重要作用。本文从酶蛋白质序列出发,以位点氨基酸和20种氨基酸n-gap 2肽组分为参数,首次将矩阵打分的方法用于酶蛋白质中8类二级结构的识别,预测总精度Q8最高达到61.4%。
Enzymes are a kind of protein that has catalytic function. The study of secondary structures in en-zymes plays an important role in the structure and function of enzymes. Based on enzyme protein sequence information, amino acids of sites and n-gap dipeptide composition of twenty amino acids were selected as parameters. Scoring matrix method was first applied to the identification of 8-state secondary structure in enzymes protein. The prediction accuracy of Q8 reached 61.4%.
出处
《生物医学》
CAS
2021年第4期214-219,共6页
Hans Journal of Biomedicine
