摘要
<strong>Background</strong><strong>:</strong><b><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">Septic shock is a rapidly changing and fatal syndrome that can </span><span style="font-family:Verdana;">cause comprehensive deterioration of cardiopulmonary and renal function and multiple organ failure. At the same time, septic shock has the complex clinical manifestations and hemodynamics. PiCCO can accurately </span><span style="font-family:Verdana;">monitor blood flow, physical and volume indicators, and active and effective fluid resuscitation are important measures to reduce the fatality rate of septic shock and improve the prognosis of patients. </span><b><span style="font-family:Verdana;">Objectives: </span></b><span style="font-family:Verdana;">To explore the application an</span><span style="font-family:Verdana;">d nursing of PiCCO in early fluid resuscitation in patie</span><span style="font-family:Verdana;">nts with septic shock. </span><b><span style="font-family:Verdana;">Me</span><span style="font-family:Verdana;">thods:</span></b><span style="font-family:Verdana;"> This was a retrospective observ</span><span style="font-family:Verdana;">ational study. The observation group and the control group each had 30 cases. The observation group used PiCCO to guide fluid resuscitation;the control group used conventional methods to guide fluid resuscitation.</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The changes in CVP, HR, MAP, and urine volume per hour were observed in the two groups. The changes of various indicators before and after fluid resuscitation, the length of stay in ICU and the mortality rate were compared between the two groups. All the outcomes were collected from the electronic medical case system after patients’ discharge from the hospital. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">APACHE </span></span><span style="font-family:Verdana;">II</span><span style="font-family:;" "=""><span style="font-family:Verdana;">, CVP, HR, MAP were compared between th</span><span style="font-family:Verdana;">e obse</span><span style="font-family:Verdana;">rvation group and th</span></span><span style="font-family:;" "=""><span style="font-family:Verdana;">e control group, and the differences w</span><span><span style="font-family:Verdana;">ere statistically significant (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.05). The blood volume of patients in the observatio</span><span style="font-family:;" "=""><span style="font-family:Verdana;">n group was significantly improved after fluid supplementation</span><span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.05). Compared with the control group, the length of stay in ICU in the observation group was significantly shorter, and the mortality rate was also significantly reduced</span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span><span> </span><span style="font-family:Verdana;"><</span><span> </span><span style="font-family:Verdana;">0.05</span><span><span style="font-family:Verdana;">). </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> PiCCO can be better used in early fluid resuscitation of patients with septic shock.</span></span>
<strong>Background</strong><strong>:</strong><b><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">Septic shock is a rapidly changing and fatal syndrome that can </span><span style="font-family:Verdana;">cause comprehensive deterioration of cardiopulmonary and renal function and multiple organ failure. At the same time, septic shock has the complex clinical manifestations and hemodynamics. PiCCO can accurately </span><span style="font-family:Verdana;">monitor blood flow, physical and volume indicators, and active and effective fluid resuscitation are important measures to reduce the fatality rate of septic shock and improve the prognosis of patients. </span><b><span style="font-family:Verdana;">Objectives: </span></b><span style="font-family:Verdana;">To explore the application an</span><span style="font-family:Verdana;">d nursing of PiCCO in early fluid resuscitation in patie</span><span style="font-family:Verdana;">nts with septic shock. </span><b><span style="font-family:Verdana;">Me</span><span style="font-family:Verdana;">thods:</span></b><span style="font-family:Verdana;"> This was a retrospective observ</span><span style="font-family:Verdana;">ational study. The observation group and the control group each had 30 cases. The observation group used PiCCO to guide fluid resuscitation;the control group used conventional methods to guide fluid resuscitation.</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The changes in CVP, HR, MAP, and urine volume per hour were observed in the two groups. The changes of various indicators before and after fluid resuscitation, the length of stay in ICU and the mortality rate were compared between the two groups. All the outcomes were collected from the electronic medical case system after patients’ discharge from the hospital. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">APACHE </span></span><span style="font-family:Verdana;">II</span><span style="font-family:;" "=""><span style="font-family:Verdana;">, CVP, HR, MAP were compared between th</span><span style="font-family:Verdana;">e obse</span><span style="font-family:Verdana;">rvation group and th</span></span><span style="font-family:;" "=""><span style="font-family:Verdana;">e control group, and the differences w</span><span><span style="font-family:Verdana;">ere statistically significant (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.05). The blood volume of patients in the observatio</span><span style="font-family:;" "=""><span style="font-family:Verdana;">n group was significantly improved after fluid supplementation</span><span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.05). Compared with the control group, the length of stay in ICU in the observation group was significantly shorter, and the mortality rate was also significantly reduced</span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span><span> </span><span style="font-family:Verdana;"><</span><span> </span><span style="font-family:Verdana;">0.05</span><span><span style="font-family:Verdana;">). </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> PiCCO can be better used in early fluid resuscitation of patients with septic shock.</span></span>
作者
Shunling Li
Surui Liang
Weihua Xue
Shunling Li;Surui Liang;Weihua Xue(The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China;Nethersole School of Nursing, Faculty of Medicine, Nethersole School of Nursing, Hong Kong, China)
