摘要
<strong>Introduction:</strong> Cryofrequency is a novel therapy which was developed with the combination of cold (cryotherapy) and heat (radiofrequency) application, causing a thermal shock effect on skin tissue. The thermal shock is believed to alter local metabolism. <strong>Objective:</strong> To investigate the effect of cryofrequency on the skin tissue of a mini pig in an <em>in vitro </em>and <em>in vivo</em> experimental model. <strong>Methodology:</strong> A small swine of the <em>S. domesticus </em>species, a male mini-pig (30 kg weight) was elected for the <em>in vivo</em> procedure subject. The <em>in vitro</em> step was performed on the extracted abdominal part of another subject of the same species and breed. Then, after the application of cryofrequency in the monopolar and bipolar form <em>in vivo</em>, a histological analysis was performed. <strong>Results: </strong>A higher temperature variation was observed comparing the pilot study <em>in vitro </em>with respect to the experimental one <em>in vivo</em>. Microscopically, an increase of collagen fibers and blood supply and decreased adipose tissue was observed after cryofrequency application. <strong>Conclusion:</strong> With the bipolar cryofrequency, no reduction of adipose tissue was observed, but regarding the connective tissue, extensive areas of collagen deposition were observed, as well as a great amount of new-formed collagen fibers.
<strong>Introduction:</strong> Cryofrequency is a novel therapy which was developed with the combination of cold (cryotherapy) and heat (radiofrequency) application, causing a thermal shock effect on skin tissue. The thermal shock is believed to alter local metabolism. <strong>Objective:</strong> To investigate the effect of cryofrequency on the skin tissue of a mini pig in an <em>in vitro </em>and <em>in vivo</em> experimental model. <strong>Methodology:</strong> A small swine of the <em>S. domesticus </em>species, a male mini-pig (30 kg weight) was elected for the <em>in vivo</em> procedure subject. The <em>in vitro</em> step was performed on the extracted abdominal part of another subject of the same species and breed. Then, after the application of cryofrequency in the monopolar and bipolar form <em>in vivo</em>, a histological analysis was performed. <strong>Results: </strong>A higher temperature variation was observed comparing the pilot study <em>in vitro </em>with respect to the experimental one <em>in vivo</em>. Microscopically, an increase of collagen fibers and blood supply and decreased adipose tissue was observed after cryofrequency application. <strong>Conclusion:</strong> With the bipolar cryofrequency, no reduction of adipose tissue was observed, but regarding the connective tissue, extensive areas of collagen deposition were observed, as well as a great amount of new-formed collagen fibers.
作者
Rafaella Rêgo Maia
Patrícia Froes Meyer
Josebel da Costa Emerenciano
Joseela Joyce Barbosa da Silva
Júlio Davi Costa e Silva
Liliane Santos de Vasconcellos
Rodrigo Marcel Valentim da Silva
Tarciso Bruno Montenegro Sampaio
Ciro Dantas Soares
Rafaella Rêgo Maia;Patrícia Froes Meyer;Josebel da Costa Emerenciano;Joseela Joyce Barbosa da Silva;Júlio Davi Costa e Silva;Liliane Santos de Vasconcellos;Rodrigo Marcel Valentim da Silva;Tarciso Bruno Montenegro Sampaio;Ciro Dantas Soares(Federal Universityof Rio Grande do Norte (UFRN), Natal, Brazil;University Centre of Rio Grande do Norte (UNI-RN), Natal, Brazil;Potiguar University (UNP), Natal, Brazil;Maurício de Nassau College, Natal, Brazil;Universityof Campinas (UNICAMP), São Paulo, Brazil)
