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Progress in the Study of the Correlation between Apolipoproteins and Endometrial Cancer 被引量:1

Progress in the Study of the Correlation between Apolipoproteins and Endometrial Cancer
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摘要 In recent years, Lipid metabolism disorder has been closely related to malignant tumors. Apolipoprotein (Apo), as an important protein in lipoprotein transport and metabolism, plays an important role in the process of tumor proliferation. Endometrial carcinoma (EC) is a common gynecological malignant tumor, and its incidence is increasing year by year;in which obesity is an independent risk factor for the occurrence and prognosis of EC. This paper discusses the correlation and possible mechanism between different types of Apo and the occurrence, development and prognosis of EC, and briefly reviews the clinical application of some drugs in EC. In recent years, Lipid metabolism disorder has been closely related to malignant tumors. Apolipoprotein (Apo), as an important protein in lipoprotein transport and metabolism, plays an important role in the process of tumor proliferation. Endometrial carcinoma (EC) is a common gynecological malignant tumor, and its incidence is increasing year by year;in which obesity is an independent risk factor for the occurrence and prognosis of EC. This paper discusses the correlation and possible mechanism between different types of Apo and the occurrence, development and prognosis of EC, and briefly reviews the clinical application of some drugs in EC.
作者 Luqing Lou Haibin Zhu Luqing Lou;Haibin Zhu(Department of Obstetrics and Gynecology, College of Medicine, Zhejiang University, Hangzhou, China;Department of Gynecology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China)
出处 《Journal of Biosciences and Medicines》 CAS 2022年第12期110-121,共12页 生物科学与医学(英文)
关键词 Endometrial Carcinoma APOLIPOPROTEIN CARCINOGENESIS Endometrial Carcinoma Apolipoprotein Carcinogenesis
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  • 1Ho Y Y, Deckelbaum R J, Chen Y, et al. Apolipopro- tein E inhibits serum-stimulated cell proliferation and en- hances serum-independent cell proliferation [ J]. J Biol Chem, 2001,276(46) :43455-43462.
  • 2O'neil C H, Boffa M B, Hancock M A, et al. Stimulation of vascular smooth muscle cell proliferation and migration by apolipoprotein(a) is dependent on inhibition of trans- forming growth factor-beta activation and on the presence of kringle IV type 9 [ J ]. J Biol Chem, 2004,279 ( 53 ) : 55187-55195.
  • 3Lynch J R, Morgan D, Mance J, et al. Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response [ J]. J Neuroimmu- nol, 2001,114(1-2) :107-113.
  • 4Urquidi V, Goodison S, Ross S, et al. Diagnostic poten- tial of urinary ctl-antitrypsin and apolipoprotein E in the detection of bladder cancer [ J ]. J Urol, 2012,188 (6) : 2377-2383.
  • 5Kulminski A M, Arbeev K G, Culminskaya I, et al. Age, gender, and cancer but not neurodegenerative and cardio- vascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan [ J ]. PLoS Genet,2014,10 ( 1 ) : e1004141.
  • 6Ivanova T I, Krikunova L I, Ryabchenko N I, et al. As- sociation of the apolipoprotein E 2 allele with concurrent occurrence of endometrial hyperplasia and endometrial carcinoma [ J]. Oxid Med Cell Longev, 2015, 2015: 593658.
  • 7Liu Z, Gao Y, Hao F, et al. Secretomes are a potential source of molecular targets for cancer therapies and indi- cate that ApoE is a candidate biomarker for lung adeno- carcinoma metastasis[ J ]. Mol Biol Rep, 2014,41 ( 11 ) : 7507 -7523.
  • 8Chen J, Chen L J, Yang R B, et al. Expression and clinical significance of apolipoprotein E in pancreatic duc- tal adenocarcinoma[ J~. Med Oncol, 2013,30(2) :583.
  • 9Wang Y, Chen Z, Chen J, et al. The diagnostic value of apolipoprotein E in malignant pleural effusion associated with non-small cell lung cancer [ J ]. Clin Chim Acta, 2013,421:230-235.
  • 10Gabrilovich D I, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system [ J ]. Nat Rev Im- munol, 2009,9( 3 ) : 162-174.

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