摘要
<strong>Introduction:</strong><span style="font-family:Verdana;"> Peripartum cardiomyopathy (PPCM) is a heart failure whose etiology is still unknown. </span><span style="font-family:Verdana;">The a</span><span style="font-family:Verdana;">im</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">of work was to study peripartum cardiomyopathy in its epidemiological, clinical, paraclinical and therapeutic aspects at the Tombouctou hospital.</span><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This is a descriptive cross-sectional study carried out in the Medicine Department of the Timbuktu hospital from January 1 to December 31, 2019. It concerned patients who presented heart failure between the 8th month of pregnancy and the first 5 months postpartum.</span><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">D</span><span style="font-family:Verdana;">uring the study</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">23 patients were collected. Average age of the patients was 23.50 ± 3.50 years with extremes of 16 and 34 years. Incidence of Peripartum cardiomyopathy (PPCM) was 1/345 pregnancies. Average parity was 3.20 with extremes of 1 and 8. Symptoms appeared at postpartum with 87% of cases. A significant delay in diagnosis was observed. Global heart failure was the mode of decompensation with 70%. Electrocardiographic signs were mainly sinus tachycardia (87%) and left ventricular hypertrophy (83%). Cardiac ultrasound showed in all cases dilated cardiomyopathy and it was associated with thrombus in left ventricle cavity for three cases. Left ventricular ejection fraction was severely impaired in 70% of cases. Pulmonary hypertension was significant in 52%.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">Most commonly drugs we used in our series at acute stage were duretics: furosemide 100% and spironolactone 70% (100% and 70%) and ACE inhibitors (90%). Beta-blockers (bisoprolol and carvedilol) were used in 15 patients. Bromocriptine (prolactin inhibitor) was used for 2 patients.</span><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Peripartum cardiomyopathy is a serious cardiac complication of pregnancy of unknown cause, common in the African population.</span>
<strong>Introduction:</strong><span style="font-family:Verdana;"> Peripartum cardiomyopathy (PPCM) is a heart failure whose etiology is still unknown. </span><span style="font-family:Verdana;">The a</span><span style="font-family:Verdana;">im</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">of work was to study peripartum cardiomyopathy in its epidemiological, clinical, paraclinical and therapeutic aspects at the Tombouctou hospital.</span><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This is a descriptive cross-sectional study carried out in the Medicine Department of the Timbuktu hospital from January 1 to December 31, 2019. It concerned patients who presented heart failure between the 8th month of pregnancy and the first 5 months postpartum.</span><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">D</span><span style="font-family:Verdana;">uring the study</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">23 patients were collected. Average age of the patients was 23.50 ± 3.50 years with extremes of 16 and 34 years. Incidence of Peripartum cardiomyopathy (PPCM) was 1/345 pregnancies. Average parity was 3.20 with extremes of 1 and 8. Symptoms appeared at postpartum with 87% of cases. A significant delay in diagnosis was observed. Global heart failure was the mode of decompensation with 70%. Electrocardiographic signs were mainly sinus tachycardia (87%) and left ventricular hypertrophy (83%). Cardiac ultrasound showed in all cases dilated cardiomyopathy and it was associated with thrombus in left ventricle cavity for three cases. Left ventricular ejection fraction was severely impaired in 70% of cases. Pulmonary hypertension was significant in 52%.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">Most commonly drugs we used in our series at acute stage were duretics: furosemide 100% and spironolactone 70% (100% and 70%) and ACE inhibitors (90%). Beta-blockers (bisoprolol and carvedilol) were used in 15 patients. Bromocriptine (prolactin inhibitor) was used for 2 patients.</span><span style="font-family:Verdana;"> </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Peripartum cardiomyopathy is a serious cardiac complication of pregnancy of unknown cause, common in the African population.</span>
作者
Souleymane Mariko
Massama Konaté
Samba Sidibé
Karamoko Kantako
Charles Dara
Djibril Kassogué
Nouhoum Diallo
Coumba A. Thiam
Aniessa Kodio
Mariam Sako
Abdoul Karim Sacko
Mamadou Diakité
Souleymane Coulibaly
Ilo Bella Diall
Ichaka Menta
Souleymane Mariko;Massama Konaté;Samba Sidibé;Karamoko Kantako;Charles Dara;Djibril Kassogué;Nouhoum Diallo;Coumba A. Thiam;Aniessa Kodio;Mariam Sako;Abdoul Karim Sacko;Mamadou Diakité;Souleymane Coulibaly;Ilo Bella Diall;Ichaka Menta(General Medicine Service, Tombouctou Hospital, Tombouctou, Mali;Cardiology Department, Mali Hospital, Bamako, Mali;Cardiology Department Point G Hospital University Center, Bamako, Mali;Department of Pediatrics, Tombouctou Hospital, Tombouctou, Mali;Cardiology Department Kati Hospital University Center, Kati, Mali;Cardiology Department, Ségou Hospital, Ségou, Mali;Cardiology Department Gabriel Touré Hospital University Center, Bamako, Mali)
