摘要
Several quinolino-benzoxaborole derivatives have been prepared to start from aminobenzoxaboroles. These derivatives have been evaluated for their anti-cancer activity on human and murine cancer cell lines and based on their relative non-toxicity, these compounds were further evaluated for their antibacterial activity against E. coli, B. subtilis, and M. smegmatis. The synthesized compounds were also evaluated for antifungal activity in C. albicans and C. neoformans.
Several quinolino-benzoxaborole derivatives have been prepared to start from aminobenzoxaboroles. These derivatives have been evaluated for their anti-cancer activity on human and murine cancer cell lines and based on their relative non-toxicity, these compounds were further evaluated for their antibacterial activity against E. coli, B. subtilis, and M. smegmatis. The synthesized compounds were also evaluated for antifungal activity in C. albicans and C. neoformans.
作者
Greeshma P. Kumpati
Michael J. Williams
Srinidhi Mereddy
Joseph L. Johnson
Shirisha Jonnalagadda
Greeshma P. Kumpati;Michael J. Williams;Srinidhi Mereddy;Joseph L. Johnson;Shirisha Jonnalagadda(Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, USA;Department of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN, USA;Department of Biology, University of Washington, Seattle, WA, USA)
