摘要
目的 探讨在心力衰竭合并肺炎的老年患者中,血清检测NT-pro BNP以及PCT的水平与患者的预后的相关性.方法 选取2015年1月至2017年12月老年患者75例,其临床诊断为心衰合并肺炎,根据预后分成死亡组和存活组.在入组患者住院的整个过程中,将两组患者在入院后1d、2d、3d、5d、7d以及出院或者死亡当天的血清PCT、NT-pro-BNP水平详细记录,并进行统计分析.结果 入组患者的临床一般资料差异无统计学意义.存活组的血清PCT水平在1d与死亡组差异无统计学意义(P>0.05),从2d开始与死亡组差异有统计学意义(P<0.05),存活组显著比死亡组水平低.存活组的血清NT-pro-BNP在1d与死亡组差异无统计学意义(P>0.05),从2d开始与死亡组差异有统计学意义(P<0.05),存活组显著比死亡组水平低.结论 血清中的PCT、NT-pro-BNP水平作为一项评价指标,对于心力衰竭合并肺炎的老年患者的严重程度以及预后有一定的临床意义,能够预测患者的预后,并且指导患者的临床治疗.
Objective To investigate the correlation between the serum levels of NT-pro BNP and PCT in elderly patients with heart failure and pneumonia. Methods 75 elderly patients who were treated or hospitalized were selected in our hospital from January 2015 to December 2017. Their clinical diagnosis were heart failure and pneumonia,and they were divided into death group and survival group according to the prognosis. In the entire course of hospitalization of enrolled patients,the serum PCT,NT-pro-of the two groups of patients on the first day,the second day,the third day,the fifth day,the seventh day after admission,and the day of discharge or death were detailed recorded of BNP levels and statistical analyzed. Results There was no statistically significant difference in the general clinical data of the enrolled patients. The serum PCT in the surviving group was not different from that in the death group on day d1(P>0.05),and was statistically different from the death group from 2d(P<0.05). The survival group was significantly lower than the death group. The serum NT-pro-BNP in the surviving group was not different from that in the death group on 1d (P>0.05),and was statistically different from the death group from 2d(P<0.05). The survival group was significantly lower than the death group. Conclusion Serum PCT and NT-pro-BNP levels as evaluation indexes have certain clinical significance for the severity and prognosis of elderly patients with heart failure complicated with pneumonia,can predict the prognosis of patients,and guide clinical treatment of patients.
出处
《浙江临床医学》
2018年第12期2032-2033,共2页
Zhejiang Clinical Medical Journal
