本文总结了1例椎管内占位合并不完全瘫痪同时伴有慢性阻塞性肺疾病患者的全面护理过程及成效。该患者先后施行了椎管内病损切除术以及胸椎内固定术。在整个治疗与护理期间,通过采取一系列针对性的护理措施,患者的呼吸功能得到了全程的...本文总结了1例椎管内占位合并不完全瘫痪同时伴有慢性阻塞性肺疾病患者的全面护理过程及成效。该患者先后施行了椎管内病损切除术以及胸椎内固定术。在整个治疗与护理期间,通过采取一系列针对性的护理措施,患者的呼吸功能得到了全程的有效改善,从术前的呼吸不畅逐渐转变为呼吸平稳顺畅。术后,患者双下肢的感觉逐渐恢复敏锐,肌力也逐步增强,从最初的无力状态到能够进行一定程度的自主活动。此外,护理团队通过积极有效的预防措施,成功避免了深静脉血栓的形成,极大地降低了患者面临的潜在风险。经过精心护理,患者的神经肌肉功能得到了显著改善,身体机能得以逐步恢复,生活质量大幅提升。最终,患者在医护人员的共同努力下好转出院,为类似病例的护理提供了宝贵的经验借鉴。This article summarizes the comprehensive care process and effectiveness of a patient with neuraxial mass combined with incomplete paralysis and chronic obstructive pulmonary disease. The patient underwent neuraxial resection and thoracic fixation. During the whole treatment and nursing period, through a series of targeted nursing measures, the patient’s respiratory function was effectively improved throughout the whole process, and the breathing gradually changed from poor breathing before surgery to stable and smooth breathing. After the operation, the patient’s sensations in both lower limbs gradually regained sharpness, and the muscle strength gradually increased, from the initial state of weakness to the ability to perform a certain degree of autonomous movement. In addition, the nursing team successfully avoided the formation of deep vein thrombosis through proactive and effective preventive measures, greatly reducing the potential risks faced by patients. After careful care, the patient’s neuromuscular function has been significantly improved, physical functions have been gradually restored, and the quality of life has been greatly improved. In the end, the patient was discharged from the hospital with the joint efforts of the medical staff, which provided valuable experience for the care of similar cases.展开更多
本研究通过对1例胸椎黄韧带骨化术后合并脑脊液漏患者的护理情况进行了总结。该患者接受胸椎后路椎板切除术后,出现脑脊液漏这一状况。面对此情况,医护团队迅速行动。在抗感染治疗上,依据患者具体状况精准选用抗生素,密切监测相关指标...本研究通过对1例胸椎黄韧带骨化术后合并脑脊液漏患者的护理情况进行了总结。该患者接受胸椎后路椎板切除术后,出现脑脊液漏这一状况。面对此情况,医护团队迅速行动。在抗感染治疗上,依据患者具体状况精准选用抗生素,密切监测相关指标变化。对于引流管道,护理人员按时检查其通畅性,留意引流液情况,严格无菌操作,保障引流顺利且安全。同时,还为患者制定全面个体化护理方案,从协助翻身、拍背预防并发症,到耐心疏导情绪,再到搭配合理膳食保证营养摄入,全方位关怀。通过这些积极有效的护理举措,成功控制了患者术后脑脊液漏感染问题,患者最终痊愈出院,生活质量也得以提高,此次护理也为类似病例积累了宝贵经验。This study summarized the nursing status of a patient with cerebrospinal fluid leakage after ossification of the ligamentum flavum in the thoracic spine. The patient underwent posterior thoracic laminectomy and had cerebrospinal fluid leakage. Faced with this situation, the medical team acted quickly. In terms of anti-infective treatment, antibiotics are accurately selected according to the specific condition of patients, and changes in relevant indicators are closely monitored. For the drainage pipeline, the nursing staff checks its patency on time, pays attention to the drainage fluid, and strictly aseptic operation to ensure the smooth and safe drainage. At the same time, it also formulates a comprehensive individualized care plan for patients, from assisting in turning over, patting the back to prevent complications, to patiently channeling emotions, to matching a reasonable diet to ensure nutritional intake, all-round care. Through these active and effective nursing measures, the patient’s postoperative cerebrospinal fluid leakage infection was successfully controlled, and the patient was finally cured and discharged from the hospital, and the quality of life was also improved.展开更多
腰椎间盘突出症是一种常见的脊柱疾病,教育患者对疾病和康复的理解至关重要。本综述探讨了不同健康教育模型在腰椎间盘突出症患者教育中的应用。Teachback法和思维导图等交互式教育模式能提高患者对康复信息的理解和记忆,增强自我管理...腰椎间盘突出症是一种常见的脊柱疾病,教育患者对疾病和康复的理解至关重要。本综述探讨了不同健康教育模型在腰椎间盘突出症患者教育中的应用。Teachback法和思维导图等交互式教育模式能提高患者对康复信息的理解和记忆,增强自我管理能力。然而,应用这些方法在实际临床中面临着一些挑战和限制,包括培训医务人员需具备高技能水平、需要更多资源和时间,以及个体差异可能影响教育效果。未来研究需关注长期效果和实际应用的可行性,以优化腰椎间盘突出症患者的健康教育策略。选择适当的健康教育模型应考虑患者的需求,以提升康复效果和患者满意度。Lumbar disc herniation is a common spinal disorder, and educating patients about the disease and rehabilitation is crucial. This review examines the application of different health education models in the education of patients with lumbar disc herniation. Interactive education models such as the Teachback method and mind mapping can improve patients’ understanding and retention of rehabilitation information and enhance self-management skills. However, the application of these methods faces some challenges and limitations in actual clinical practice, including the need for a high skill level to train medical staff, the need for more resources and time, and the possibility that individual differences may affect educational outcomes. Future studies need to focus on the long-term effects and feasibility of practical application to optimize health education strategies for patients with lumbar disc herniation. Selection of appropriate health education models should take into account the needs of patients to enhance rehabilitation outcomes and patient satisfaction.展开更多
目的:通过查阅预防性使用万古霉素粉末手术比较的文献,对该方法在脊柱手术后降低感染率的效果做出系统评价,为以后的临床工作提供依据。方法:通过Pubmed,Medline,Elseveir,万方,CNKI等数据库,以“vancomycin”,“local/intraoperative/t...目的:通过查阅预防性使用万古霉素粉末手术比较的文献,对该方法在脊柱手术后降低感染率的效果做出系统评价,为以后的临床工作提供依据。方法:通过Pubmed,Medline,Elseveir,万方,CNKI等数据库,以“vancomycin”,“local/intraoperative/topical/intra-wound”,“spine/spinal/lumbar/cervical/thoracolumbar surgery”,“infection”,“SSI”,“脊柱”,“腰椎”,“颈椎”,“手术”,“万古霉素”,“感染”等关键词查找相关术中预防性应用万古霉素粉末对术后感染发生率影响方面的病例对照研究论文,并利用Revman5.3荟萃分析软件比较文献中总体感染率,并按不同亚组分析是否应用万古霉素对不同部位、不同类型的脊柱手术的感染率的影响。结果:共查出论文1713篇,其中病例对照试验有38篇,最后筛选出符合要求的文献25篇;有25个研究比较了预防性使用万古霉素粉末对脊柱手术后感染率的影响。总病例16,688例,其中预防性使用万古霉素组7048例,对照组9640例。其荟萃分析结果提示术中预防性使用万古霉素粉末后术后出现感染的可能性为不使用万古霉素时的0.38倍,二者之间的差异有显著性(P Objective: To systematically evaluate the effect of this method in reducing the infection rate after spinal surgery by reviewing the comparative literature of prophylactic vancomycin powder surgery, so as to provide a basis for future clinical work. Methods: Pubmed, Medline, Elseveir, Wanfang, CNKI and other databases, with the following methods: “vancomycin”, “local/intraoperative/topical/intra-wound”, “spine/spinal/lumbar/cervical/thoracolumbar surgery”, “infection”, “SSI”, “spine”, “lumbar spine”, “cervical spine”, “surgery”, “vancomycin”, “infection” and other keywords were used to find case-control research papers on the effect of intraoperative prophylactic vancomycin powder on the incidence of postoperative infection, and the Revman5.3 meta-analysis software was used to compare the overall infection rate in the literature, and the effect of vancomycin application on the infection rate of different parts and different types of spine surgery was analyzed according to different subgroups. Results: A total of 1713 papers were identified, including 38 case-control trials, and 25 papers were screened to meet the requirements. Twenty-five studies compared the effect of prophylactic use of vancomycin powder on infection rates after spinal surgery. The total number of cases was 16,688, including 7048 cases in the prophylactic vancomycin group and 9640 cases in the control group. The results of meta-analysis showed that the probability of postoperative infection after intraoperative prophylactic use of vancomycin powder was 0.38 times higher than that of vancomycin without vancomycin, and the difference between the two was significant (P < 0.01). At the same time, the incidence of infection after vancomycin was 0.28 times higher (0.17, 0.45) than that of vancomycin in patients treated with internal fixation (P < 0.01). However, vancomycin utilization in patients without internal fixation had no significant effect on postoperative infection (P = 0.61). Conclusion: The local prophylactic use of vancomycin powder in spine surgery can significantly reduce the incidence of postoperative infection, and this effect is more obvious in patients with internal fixation, which can be popularized and applied in clinical practice of spine surgery.展开更多
丹参酮IIA (Tanshinone IIA, TanIIA)是从中药丹参中提取的主要有效成分之一,研究表明其在抗炎、抗氧化、抗肿瘤、心脏保护及神经系统保护方面具有显著的药理活性。本文采用文献计量学的方法,对国内外有关丹参酮IIA的研究进行分析,发现...丹参酮IIA (Tanshinone IIA, TanIIA)是从中药丹参中提取的主要有效成分之一,研究表明其在抗炎、抗氧化、抗肿瘤、心脏保护及神经系统保护方面具有显著的药理活性。本文采用文献计量学的方法,对国内外有关丹参酮IIA的研究进行分析,发现丹参酮IIA的研究是基于2000年至2024年间发表的13,681篇有关丹参酮IIA的文献的计量学分析;该领域发表研究论文最多的国家是中国,美国和澳大利亚,而发表论文最多的机构为中国医科大学,中国科学院和中山大学。丹参酮IIA在心血管疾病和神经系统疾病中的研究文献占比最高,研究类型主要以应用基础研究,临床研究和技术开发为主,出现频率最多的关键词为凋亡,表达,激活,氧化应激,炎症反应等,体现了其在这些领域的研究热度和临床应用价值。丹参酮IIA作为一种具有多重药理活性的中药成分,显示出广泛的临床应用前景,而当前研究的局限性和挑战需要我们在未来的研究中予以重视,通过多学科合作和创新研究方法,共同推动丹参酮IIA在疾病治疗中的进一步应用与发展。Tanshinone IIA (TanIIA) is one of the main active ingredients extracted from the traditional Chinese medicine Danshen, and studies have shown that it has significant pharmacological activities in anti-inflammatory, antioxidant, anti-tumor, cardioprotective and nervous system protection. In this paper, bibliometric methods were used to analyze the studies on tanshinone IIA at home and abroad, and found that the research on tanshinone IIA was based on quantitative analysis of 13,681 articles on tanshinone IIA published between 2000 and 2024. The countries with the most published research papers in this field are China, United States and Australia, while the institutions with the most published papers are China Medical University, Chinese Academy of Sciences and Sun Yat-sen University. Tanshinone IIA has the highest proportion of research literature in cardiovascular diseases and nervous system diseases, and the research types are mainly applied basic research, clinical research and technology development, and the most frequent keywords are apoptosis, expression, activation, oxidative stress, inflammatory response, etc., reflecting its research enthusiasm and clinical application value in these fields. As a traditional Chinese medicine ingredient with multiple pharmacological activities, tanshinone IIA has shown a wide range of clinical application prospects, but the limitations and challenges of current research need to be paid attention to in future research, and jointly promote the further application and development of tanshinone IIA in disease treatment through multidisciplinary cooperation and innovative research methods.展开更多
背景:随着元宇宙的出现,虚拟现实作为一种数字技术,必定变得越来越热门。高质量的虚拟现实相关护理知识场景学习正逐渐取代传统的教育和干预技能。目标:本系统研究旨在深入了解虚拟现实技术在护理研究中的整体应用情况。方法:研究使用了...背景:随着元宇宙的出现,虚拟现实作为一种数字技术,必定变得越来越热门。高质量的虚拟现实相关护理知识场景学习正逐渐取代传统的教育和干预技能。目标:本系统研究旨在深入了解虚拟现实技术在护理研究中的整体应用情况。方法:研究使用了从Web of Science核心合集数据库下载的关于2000年1月1日至2024年7月期间发布的虚拟现实在护理领域应用的引用文献信息。信息检索分析工具包括https://bibliometric.com/app和VOS viewer。结果:共498个机构来自95个地区贡献了相关出版物,其中美国是该研究领域最具影响力的国家。从引用的文献中获得了被引文献的聚类标签。虚拟仿真、虚拟学习、临床技能和痴呆症是共同被引文献的聚类标签。结论:虚拟护理对护士和患者都产生了影响。随着元宇宙概念的出现,虚拟现实技术在护理中的研究和应用将逐渐增加。Background: With the advent of the metaverse, virtual reality is bound to become more and more popular as a digital technology. High-quality virtual reality-related nursing knowledge and scenario-based learning is gradually replacing traditional education and intervention skills. Objective: This systematic study aims to gain insight into the overall application of virtual reality technology in nursing research. Methods: The study used citation information on the use of virtual reality in nursing published between January 1, 2000 and July 2024 from the Web of Science Core Collection database. Information retrieval and analysis tools include https://bibliometric.com/app and VOS viewer. Results: A total of 498 institutions from 95 regions contributed relevant publications, with United States being the most influential country in this research field. Clustering tags of cited documents were obtained from the cited documents. Virtual simulation, virtual learning, clinical skills, and dementia are cluster labels for co-cited articles. Conclusion: Virtual care has had an impact on both nurses and patients. With the advent of the metaverse concept, the research and application of virtual reality technology in nursing will gradually increase.展开更多
丹参酮IIA,也称为TanIIA,在生物体内代谢过程中扮演着多重角色,其产物能够影响多种生物化学反应。这些反应中,TanIIA有时作为辅酶参与,有时则可能促进或干扰这些反应过程,从而展现出多样的药理特性。尽管在脊髓损伤等神经系统疾病的治疗...丹参酮IIA,也称为TanIIA,在生物体内代谢过程中扮演着多重角色,其产物能够影响多种生物化学反应。这些反应中,TanIIA有时作为辅酶参与,有时则可能促进或干扰这些反应过程,从而展现出多样的药理特性。尽管在脊髓损伤等神经系统疾病的治疗中,TanIIA已经显示出了一定的疗效,但其具体的作用机制尚未完全阐明。基于现有的研究成果,我们推测TanIIA可能通过多种药理途径,包括抗炎、抗氧化、抗细胞凋亡以及保护血管,来促进脊髓损伤后的神经细胞存活和修复。Tanshinone IIA, also known as TanIIA, plays multiple roles in the metabolic process of living organisms, and its products can affect a variety of biochemical reactions. In these reactions, TanIIA is sometimes involved as a coenzyme, and sometimes it may facilitate or interfere with these reaction processes, thus exhibiting diverse pharmacological properties. Although TanIIA has shown some efficacy in the treatment of neurological diseases such as spinal cord injury, its specific mechanism of action has not been fully elucidated. Based on the existing research results, we speculate that TanIIA may promote the survival and repair of nerve cells after spinal cord injury through multiple pharmacological pathways, including anti-inflammatory, antioxidant, anti-apoptosis, and vascular protection.展开更多
文摘本文总结了1例椎管内占位合并不完全瘫痪同时伴有慢性阻塞性肺疾病患者的全面护理过程及成效。该患者先后施行了椎管内病损切除术以及胸椎内固定术。在整个治疗与护理期间,通过采取一系列针对性的护理措施,患者的呼吸功能得到了全程的有效改善,从术前的呼吸不畅逐渐转变为呼吸平稳顺畅。术后,患者双下肢的感觉逐渐恢复敏锐,肌力也逐步增强,从最初的无力状态到能够进行一定程度的自主活动。此外,护理团队通过积极有效的预防措施,成功避免了深静脉血栓的形成,极大地降低了患者面临的潜在风险。经过精心护理,患者的神经肌肉功能得到了显著改善,身体机能得以逐步恢复,生活质量大幅提升。最终,患者在医护人员的共同努力下好转出院,为类似病例的护理提供了宝贵的经验借鉴。This article summarizes the comprehensive care process and effectiveness of a patient with neuraxial mass combined with incomplete paralysis and chronic obstructive pulmonary disease. The patient underwent neuraxial resection and thoracic fixation. During the whole treatment and nursing period, through a series of targeted nursing measures, the patient’s respiratory function was effectively improved throughout the whole process, and the breathing gradually changed from poor breathing before surgery to stable and smooth breathing. After the operation, the patient’s sensations in both lower limbs gradually regained sharpness, and the muscle strength gradually increased, from the initial state of weakness to the ability to perform a certain degree of autonomous movement. In addition, the nursing team successfully avoided the formation of deep vein thrombosis through proactive and effective preventive measures, greatly reducing the potential risks faced by patients. After careful care, the patient’s neuromuscular function has been significantly improved, physical functions have been gradually restored, and the quality of life has been greatly improved. In the end, the patient was discharged from the hospital with the joint efforts of the medical staff, which provided valuable experience for the care of similar cases.
文摘本研究通过对1例胸椎黄韧带骨化术后合并脑脊液漏患者的护理情况进行了总结。该患者接受胸椎后路椎板切除术后,出现脑脊液漏这一状况。面对此情况,医护团队迅速行动。在抗感染治疗上,依据患者具体状况精准选用抗生素,密切监测相关指标变化。对于引流管道,护理人员按时检查其通畅性,留意引流液情况,严格无菌操作,保障引流顺利且安全。同时,还为患者制定全面个体化护理方案,从协助翻身、拍背预防并发症,到耐心疏导情绪,再到搭配合理膳食保证营养摄入,全方位关怀。通过这些积极有效的护理举措,成功控制了患者术后脑脊液漏感染问题,患者最终痊愈出院,生活质量也得以提高,此次护理也为类似病例积累了宝贵经验。This study summarized the nursing status of a patient with cerebrospinal fluid leakage after ossification of the ligamentum flavum in the thoracic spine. The patient underwent posterior thoracic laminectomy and had cerebrospinal fluid leakage. Faced with this situation, the medical team acted quickly. In terms of anti-infective treatment, antibiotics are accurately selected according to the specific condition of patients, and changes in relevant indicators are closely monitored. For the drainage pipeline, the nursing staff checks its patency on time, pays attention to the drainage fluid, and strictly aseptic operation to ensure the smooth and safe drainage. At the same time, it also formulates a comprehensive individualized care plan for patients, from assisting in turning over, patting the back to prevent complications, to patiently channeling emotions, to matching a reasonable diet to ensure nutritional intake, all-round care. Through these active and effective nursing measures, the patient’s postoperative cerebrospinal fluid leakage infection was successfully controlled, and the patient was finally cured and discharged from the hospital, and the quality of life was also improved.
文摘腰椎间盘突出症是一种常见的脊柱疾病,教育患者对疾病和康复的理解至关重要。本综述探讨了不同健康教育模型在腰椎间盘突出症患者教育中的应用。Teachback法和思维导图等交互式教育模式能提高患者对康复信息的理解和记忆,增强自我管理能力。然而,应用这些方法在实际临床中面临着一些挑战和限制,包括培训医务人员需具备高技能水平、需要更多资源和时间,以及个体差异可能影响教育效果。未来研究需关注长期效果和实际应用的可行性,以优化腰椎间盘突出症患者的健康教育策略。选择适当的健康教育模型应考虑患者的需求,以提升康复效果和患者满意度。Lumbar disc herniation is a common spinal disorder, and educating patients about the disease and rehabilitation is crucial. This review examines the application of different health education models in the education of patients with lumbar disc herniation. Interactive education models such as the Teachback method and mind mapping can improve patients’ understanding and retention of rehabilitation information and enhance self-management skills. However, the application of these methods faces some challenges and limitations in actual clinical practice, including the need for a high skill level to train medical staff, the need for more resources and time, and the possibility that individual differences may affect educational outcomes. Future studies need to focus on the long-term effects and feasibility of practical application to optimize health education strategies for patients with lumbar disc herniation. Selection of appropriate health education models should take into account the needs of patients to enhance rehabilitation outcomes and patient satisfaction.
文摘目的:通过查阅预防性使用万古霉素粉末手术比较的文献,对该方法在脊柱手术后降低感染率的效果做出系统评价,为以后的临床工作提供依据。方法:通过Pubmed,Medline,Elseveir,万方,CNKI等数据库,以“vancomycin”,“local/intraoperative/topical/intra-wound”,“spine/spinal/lumbar/cervical/thoracolumbar surgery”,“infection”,“SSI”,“脊柱”,“腰椎”,“颈椎”,“手术”,“万古霉素”,“感染”等关键词查找相关术中预防性应用万古霉素粉末对术后感染发生率影响方面的病例对照研究论文,并利用Revman5.3荟萃分析软件比较文献中总体感染率,并按不同亚组分析是否应用万古霉素对不同部位、不同类型的脊柱手术的感染率的影响。结果:共查出论文1713篇,其中病例对照试验有38篇,最后筛选出符合要求的文献25篇;有25个研究比较了预防性使用万古霉素粉末对脊柱手术后感染率的影响。总病例16,688例,其中预防性使用万古霉素组7048例,对照组9640例。其荟萃分析结果提示术中预防性使用万古霉素粉末后术后出现感染的可能性为不使用万古霉素时的0.38倍,二者之间的差异有显著性(P Objective: To systematically evaluate the effect of this method in reducing the infection rate after spinal surgery by reviewing the comparative literature of prophylactic vancomycin powder surgery, so as to provide a basis for future clinical work. Methods: Pubmed, Medline, Elseveir, Wanfang, CNKI and other databases, with the following methods: “vancomycin”, “local/intraoperative/topical/intra-wound”, “spine/spinal/lumbar/cervical/thoracolumbar surgery”, “infection”, “SSI”, “spine”, “lumbar spine”, “cervical spine”, “surgery”, “vancomycin”, “infection” and other keywords were used to find case-control research papers on the effect of intraoperative prophylactic vancomycin powder on the incidence of postoperative infection, and the Revman5.3 meta-analysis software was used to compare the overall infection rate in the literature, and the effect of vancomycin application on the infection rate of different parts and different types of spine surgery was analyzed according to different subgroups. Results: A total of 1713 papers were identified, including 38 case-control trials, and 25 papers were screened to meet the requirements. Twenty-five studies compared the effect of prophylactic use of vancomycin powder on infection rates after spinal surgery. The total number of cases was 16,688, including 7048 cases in the prophylactic vancomycin group and 9640 cases in the control group. The results of meta-analysis showed that the probability of postoperative infection after intraoperative prophylactic use of vancomycin powder was 0.38 times higher than that of vancomycin without vancomycin, and the difference between the two was significant (P < 0.01). At the same time, the incidence of infection after vancomycin was 0.28 times higher (0.17, 0.45) than that of vancomycin in patients treated with internal fixation (P < 0.01). However, vancomycin utilization in patients without internal fixation had no significant effect on postoperative infection (P = 0.61). Conclusion: The local prophylactic use of vancomycin powder in spine surgery can significantly reduce the incidence of postoperative infection, and this effect is more obvious in patients with internal fixation, which can be popularized and applied in clinical practice of spine surgery.
文摘丹参酮IIA (Tanshinone IIA, TanIIA)是从中药丹参中提取的主要有效成分之一,研究表明其在抗炎、抗氧化、抗肿瘤、心脏保护及神经系统保护方面具有显著的药理活性。本文采用文献计量学的方法,对国内外有关丹参酮IIA的研究进行分析,发现丹参酮IIA的研究是基于2000年至2024年间发表的13,681篇有关丹参酮IIA的文献的计量学分析;该领域发表研究论文最多的国家是中国,美国和澳大利亚,而发表论文最多的机构为中国医科大学,中国科学院和中山大学。丹参酮IIA在心血管疾病和神经系统疾病中的研究文献占比最高,研究类型主要以应用基础研究,临床研究和技术开发为主,出现频率最多的关键词为凋亡,表达,激活,氧化应激,炎症反应等,体现了其在这些领域的研究热度和临床应用价值。丹参酮IIA作为一种具有多重药理活性的中药成分,显示出广泛的临床应用前景,而当前研究的局限性和挑战需要我们在未来的研究中予以重视,通过多学科合作和创新研究方法,共同推动丹参酮IIA在疾病治疗中的进一步应用与发展。Tanshinone IIA (TanIIA) is one of the main active ingredients extracted from the traditional Chinese medicine Danshen, and studies have shown that it has significant pharmacological activities in anti-inflammatory, antioxidant, anti-tumor, cardioprotective and nervous system protection. In this paper, bibliometric methods were used to analyze the studies on tanshinone IIA at home and abroad, and found that the research on tanshinone IIA was based on quantitative analysis of 13,681 articles on tanshinone IIA published between 2000 and 2024. The countries with the most published research papers in this field are China, United States and Australia, while the institutions with the most published papers are China Medical University, Chinese Academy of Sciences and Sun Yat-sen University. Tanshinone IIA has the highest proportion of research literature in cardiovascular diseases and nervous system diseases, and the research types are mainly applied basic research, clinical research and technology development, and the most frequent keywords are apoptosis, expression, activation, oxidative stress, inflammatory response, etc., reflecting its research enthusiasm and clinical application value in these fields. As a traditional Chinese medicine ingredient with multiple pharmacological activities, tanshinone IIA has shown a wide range of clinical application prospects, but the limitations and challenges of current research need to be paid attention to in future research, and jointly promote the further application and development of tanshinone IIA in disease treatment through multidisciplinary cooperation and innovative research methods.
文摘背景:随着元宇宙的出现,虚拟现实作为一种数字技术,必定变得越来越热门。高质量的虚拟现实相关护理知识场景学习正逐渐取代传统的教育和干预技能。目标:本系统研究旨在深入了解虚拟现实技术在护理研究中的整体应用情况。方法:研究使用了从Web of Science核心合集数据库下载的关于2000年1月1日至2024年7月期间发布的虚拟现实在护理领域应用的引用文献信息。信息检索分析工具包括https://bibliometric.com/app和VOS viewer。结果:共498个机构来自95个地区贡献了相关出版物,其中美国是该研究领域最具影响力的国家。从引用的文献中获得了被引文献的聚类标签。虚拟仿真、虚拟学习、临床技能和痴呆症是共同被引文献的聚类标签。结论:虚拟护理对护士和患者都产生了影响。随着元宇宙概念的出现,虚拟现实技术在护理中的研究和应用将逐渐增加。Background: With the advent of the metaverse, virtual reality is bound to become more and more popular as a digital technology. High-quality virtual reality-related nursing knowledge and scenario-based learning is gradually replacing traditional education and intervention skills. Objective: This systematic study aims to gain insight into the overall application of virtual reality technology in nursing research. Methods: The study used citation information on the use of virtual reality in nursing published between January 1, 2000 and July 2024 from the Web of Science Core Collection database. Information retrieval and analysis tools include https://bibliometric.com/app and VOS viewer. Results: A total of 498 institutions from 95 regions contributed relevant publications, with United States being the most influential country in this research field. Clustering tags of cited documents were obtained from the cited documents. Virtual simulation, virtual learning, clinical skills, and dementia are cluster labels for co-cited articles. Conclusion: Virtual care has had an impact on both nurses and patients. With the advent of the metaverse concept, the research and application of virtual reality technology in nursing will gradually increase.
文摘丹参酮IIA,也称为TanIIA,在生物体内代谢过程中扮演着多重角色,其产物能够影响多种生物化学反应。这些反应中,TanIIA有时作为辅酶参与,有时则可能促进或干扰这些反应过程,从而展现出多样的药理特性。尽管在脊髓损伤等神经系统疾病的治疗中,TanIIA已经显示出了一定的疗效,但其具体的作用机制尚未完全阐明。基于现有的研究成果,我们推测TanIIA可能通过多种药理途径,包括抗炎、抗氧化、抗细胞凋亡以及保护血管,来促进脊髓损伤后的神经细胞存活和修复。Tanshinone IIA, also known as TanIIA, plays multiple roles in the metabolic process of living organisms, and its products can affect a variety of biochemical reactions. In these reactions, TanIIA is sometimes involved as a coenzyme, and sometimes it may facilitate or interfere with these reaction processes, thus exhibiting diverse pharmacological properties. Although TanIIA has shown some efficacy in the treatment of neurological diseases such as spinal cord injury, its specific mechanism of action has not been fully elucidated. Based on the existing research results, we speculate that TanIIA may promote the survival and repair of nerve cells after spinal cord injury through multiple pharmacological pathways, including anti-inflammatory, antioxidant, anti-apoptosis, and vascular protection.
