目的应用BTE Primus RS系统精确地量化刺络放血治疗膝关节炎(KOA)的临床疗效。方法选取KOA患者87例,膝关节周围压痛点予以刺络放血治疗,并使用BTE Primus RS系统对患者治疗前后膝关节功能进行客观的记录。结果刺络放血治疗后,膝关节伸...目的应用BTE Primus RS系统精确地量化刺络放血治疗膝关节炎(KOA)的临床疗效。方法选取KOA患者87例,膝关节周围压痛点予以刺络放血治疗,并使用BTE Primus RS系统对患者治疗前后膝关节功能进行客观的记录。结果刺络放血治疗后,膝关节伸肌群肌力较治疗前增长30.23%(P<0.01);功率增加307.14%(P<0.01);60°平均峰值力矩增长43.77%(P<0.01);120°平均峰值力矩增长30.78%(P<0.01)。结论刺络放血法治疗KOA具有较好的疗效,值得在临床进一步推广。展开更多
Objective： To observe the effect of different moxibustion durations on rats with rheumatoid arthritis（RA） and to evaluate the relationship between moxibustion amount and moxibustion efficacy. Methods： Eight rats w...Objective： To observe the effect of different moxibustion durations on rats with rheumatoid arthritis（RA） and to evaluate the relationship between moxibustion amount and moxibustion efficacy. Methods： Eight rats were randomly selected as a normal group from the 40 male Sprague-Dawley（SD） rats, and the other 32 rats were used to establish type Ⅱ collagen-induced RA models. After successful modeling, the 32 rats were randomly divided into a model group, a moxibustion for 20 min group, a moxibustion for 40 min group and a moxibustion for 60 min group, with 8 rats in each group. Rats in the normal group did not receive modeling and moxibustion intervention; rats in the model group did not receive moxibustion after modeling; rats in the moxibustion for 20 min group, the moxibustion for 40 min group and the moxibustion for 60 min group were treated with moxibustion at Shenshu（BL 23） and Zusanli（ST 36） for 20 min, 40 min and 60 min, respectively. Six days were a course of treatment, with a total of 3-course treatments and a 1-day rest between the courses of treatment. After treatment, the serum levels of interleukin（IL）-1β and tumor necrosis factor（TNF）-α, arthritis index（AI） scores, toe volumes and pathological score of synovitis were evaluated in the rats. Results： Compared with the normal group, the serum IL-1β and TNF-α levels, and the toe volumes in the model group were increased, and the differences were statistically significant（P〈0.01）, before the treatment. Compared with the model group, the serum IL-1β and TNF-α levels, toe volumes and arthritis index（AI） scores were significantly decreased in the moxibustion for 20 min group, the moxibustion for 40 min group and the moxibustion for 60 min group（P〈0.05 or P〈0.01）. Compared with the moxibustion for 20 min group and the moxibustion for 60 min group, serum IL-1β and TNF-α levels, toe volumes and AI scores were decreased more significantly in moxibustion for 40 min group, and the differences were statistically significant（P〈0.05 or P〈0.01）. There were no significant differences in serum IL-1β and TNF-α levels, AI scores and toe volumes between the moxibustion for 20 min group and the moxibustion for 60 min group（all P〈0.05）. The synovial histopathological improvement was the most obvious in the moxibustion for 40 min group, when the synovial histopathological changes were compared among the moxibustion for 20 min group, moxibustion for 40 min group and moxibustion for 60 min group. Conclusion： The therapeutic efficacy of moxibustion for 40 min in RA rats was more significant than that of moxibustion for 20 min and moxibustion for 60 min, indicating that the duration of moxibustion is the main factor affecting its therapeutic efficacy.展开更多
As a crucial component of acupuncture-moxibustion therapy, moxibustion has been extensively propagated and used with its significant efficacy, simple operation, inconspicuous adverse effects and less sufferings. There...As a crucial component of acupuncture-moxibustion therapy, moxibustion has been extensively propagated and used with its significant efficacy, simple operation, inconspicuous adverse effects and less sufferings. There are a variety of factors that influence the therapeutic efficacy of moxibustion. The influencing factors, including moxibustion dose （moxibustion duration, distance between moxa and skin, size and number of moxa cone）, selection of points, moxibustion sensations, and the type of moxibustion were analyzed and summarized, to provide references for approaching the maximum efficacy of moxibustion in clinic.展开更多
文摘目的应用BTE Primus RS系统精确地量化刺络放血治疗膝关节炎(KOA)的临床疗效。方法选取KOA患者87例,膝关节周围压痛点予以刺络放血治疗,并使用BTE Primus RS系统对患者治疗前后膝关节功能进行客观的记录。结果刺络放血治疗后,膝关节伸肌群肌力较治疗前增长30.23%(P<0.01);功率增加307.14%(P<0.01);60°平均峰值力矩增长43.77%(P<0.01);120°平均峰值力矩增长30.78%(P<0.01)。结论刺络放血法治疗KOA具有较好的疗效,值得在临床进一步推广。
基金supported by Qing Lan Project of Jiangsu Province,No.2014In novation Plan Project for Academic Degree Graduate Students of Colleges and Universities in Jiangsu Province,No.KYLX16_1164+1 种基金Innovation and Entrepreneurship Training Key Project for Undergraduates of Colleges and U niversities in Jiangsu Province,No.201610315015ZCommand Subject of Jiangsu Provincial Advantage Disciplines PhaseⅡProject and Nanjing University of Chinese Medicine Nursing First-level Discipline,No.YSHL2016-015~~
文摘Objective： To observe the effect of different moxibustion durations on rats with rheumatoid arthritis（RA） and to evaluate the relationship between moxibustion amount and moxibustion efficacy. Methods： Eight rats were randomly selected as a normal group from the 40 male Sprague-Dawley（SD） rats, and the other 32 rats were used to establish type Ⅱ collagen-induced RA models. After successful modeling, the 32 rats were randomly divided into a model group, a moxibustion for 20 min group, a moxibustion for 40 min group and a moxibustion for 60 min group, with 8 rats in each group. Rats in the normal group did not receive modeling and moxibustion intervention; rats in the model group did not receive moxibustion after modeling; rats in the moxibustion for 20 min group, the moxibustion for 40 min group and the moxibustion for 60 min group were treated with moxibustion at Shenshu（BL 23） and Zusanli（ST 36） for 20 min, 40 min and 60 min, respectively. Six days were a course of treatment, with a total of 3-course treatments and a 1-day rest between the courses of treatment. After treatment, the serum levels of interleukin（IL）-1β and tumor necrosis factor（TNF）-α, arthritis index（AI） scores, toe volumes and pathological score of synovitis were evaluated in the rats. Results： Compared with the normal group, the serum IL-1β and TNF-α levels, and the toe volumes in the model group were increased, and the differences were statistically significant（P〈0.01）, before the treatment. Compared with the model group, the serum IL-1β and TNF-α levels, toe volumes and arthritis index（AI） scores were significantly decreased in the moxibustion for 20 min group, the moxibustion for 40 min group and the moxibustion for 60 min group（P〈0.05 or P〈0.01）. Compared with the moxibustion for 20 min group and the moxibustion for 60 min group, serum IL-1β and TNF-α levels, toe volumes and AI scores were decreased more significantly in moxibustion for 40 min group, and the differences were statistically significant（P〈0.05 or P〈0.01）. There were no significant differences in serum IL-1β and TNF-α levels, AI scores and toe volumes between the moxibustion for 20 min group and the moxibustion for 60 min group（all P〈0.05）. The synovial histopathological improvement was the most obvious in the moxibustion for 40 min group, when the synovial histopathological changes were compared among the moxibustion for 20 min group, moxibustion for 40 min group and moxibustion for 60 min group. Conclusion： The therapeutic efficacy of moxibustion for 40 min in RA rats was more significant than that of moxibustion for 20 min and moxibustion for 60 min, indicating that the duration of moxibustion is the main factor affecting its therapeutic efficacy.
基金supported by Qing Lan Project of Jiangsu Province, No. 2014Innovation Plan Project for Academic Degree Graduate Students of Colleges and Universities in Jiangsu Province,No. KYLX16_1164+1 种基金Innovation and Entrepreneurship Training Key Project for Undergraduates of Colleges and Universities in Jiangsu Province, No. 201610315015ZCommand Subject of Jiangsu Provincial Advantage Disciplines Phase Ⅱ Project and Nanjing University of Chinese Medicine Nursing First-level Discipline, No.YSHL2016-015~~
文摘As a crucial component of acupuncture-moxibustion therapy, moxibustion has been extensively propagated and used with its significant efficacy, simple operation, inconspicuous adverse effects and less sufferings. There are a variety of factors that influence the therapeutic efficacy of moxibustion. The influencing factors, including moxibustion dose （moxibustion duration, distance between moxa and skin, size and number of moxa cone）, selection of points, moxibustion sensations, and the type of moxibustion were analyzed and summarized, to provide references for approaching the maximum efficacy of moxibustion in clinic.
