Taxol is a unique antitumor drug that appears to exert its activity as a result of interference with microtubular structure and function. The Taxol solubility of in methanol, ethanol and methanol-water was measured by...Taxol is a unique antitumor drug that appears to exert its activity as a result of interference with microtubular structure and function. The Taxol solubility of in methanol, ethanol and methanol-water was measured by the equilibrium method in this paper. The data obtained were correlated by the regress equation and ANN model. The results showed that the both were in excellent agreement with the experimental data and the ANN model was more convenient than the regress equation.展开更多
Amylanthraquinone (AAQ) is a novel,effective working carrier and a potential substitute of 2-ethylanthraquinone (EAQ) in hydrogen peroxide production process.In order to obtain the basic data for the process developme...Amylanthraquinone (AAQ) is a novel,effective working carrier and a potential substitute of 2-ethylanthraquinone (EAQ) in hydrogen peroxide production process.In order to obtain the basic data for the process development,the equilibria method was used to experimentally measure the solubility of AAQ in the mixed organic solvents of trimethylbenzen(TMB) and trioctyl phosphate(TOP) with different volume ratios,at 298.15—323.15 K. It was found that the solubility of AAQ was ca . 3 times greater than EAQ at the same conditions. Finally,experimental data were correlated by the modified λ-h equation,in which a factor of the solvent composition was added.The results showed that the modified λ-h equation can be used to predict the solubility of AAQ in TMB/TOP system with an average relative deviation (ARD) of 5%.展开更多
文摘Taxol is a unique antitumor drug that appears to exert its activity as a result of interference with microtubular structure and function. The Taxol solubility of in methanol, ethanol and methanol-water was measured by the equilibrium method in this paper. The data obtained were correlated by the regress equation and ANN model. The results showed that the both were in excellent agreement with the experimental data and the ANN model was more convenient than the regress equation.
文摘Amylanthraquinone (AAQ) is a novel,effective working carrier and a potential substitute of 2-ethylanthraquinone (EAQ) in hydrogen peroxide production process.In order to obtain the basic data for the process development,the equilibria method was used to experimentally measure the solubility of AAQ in the mixed organic solvents of trimethylbenzen(TMB) and trioctyl phosphate(TOP) with different volume ratios,at 298.15—323.15 K. It was found that the solubility of AAQ was ca . 3 times greater than EAQ at the same conditions. Finally,experimental data were correlated by the modified λ-h equation,in which a factor of the solvent composition was added.The results showed that the modified λ-h equation can be used to predict the solubility of AAQ in TMB/TOP system with an average relative deviation (ARD) of 5%.
