目的:探讨CD4^(+)/CD8^(+)比值降钙素原(Procallcitonin,PCT)、C反应蛋白(C-reactiveprotein,CRP)水平变化与感染性休克(Septicshock,SS)患者疾病转归的相关性。方法:选取我院2020年4月-2022年2月收治的135例SS患者为研究对象,根据患者...目的:探讨CD4^(+)/CD8^(+)比值降钙素原(Procallcitonin,PCT)、C反应蛋白(C-reactiveprotein,CRP)水平变化与感染性休克(Septicshock,SS)患者疾病转归的相关性。方法:选取我院2020年4月-2022年2月收治的135例SS患者为研究对象,根据患者28d疾病转归分为生存组(91例)和病死组(44例)。比较两组一般临床资料,比较两组治疗前、治疗3d、7d后CD4^(+)/CD8^(+)比值、PCT、CRP水平,分析治疗3d、7d后CD4^(+)/CD8^(+)比值、PCT、CRP水平与急性生理与慢性健康评估(Acute physiology and chronic health evaluationⅡ,APCHEⅡ)评分、序贯器官衰竭(Sepsis-related organ failure assessment,SOFA)评分及疾病转归的相关性,偏回归分析影响SS患者疾病转归的危险因素。结果:病死组年龄、治疗3d后、7d后APACHEⅡ评分、SOFA评分较生存组高(P<0.05);病死组治疗3d、7d后CD4^(+)/CD8^(+)比值低于生存组,PCT、CRP水平高于生存组(P<0.05);治疗3d、7d后,CD4+/CD8+比值与SOFA评分、APCHEⅡ评分、疾病转归呈负相关,PCT、CRP水平与SOFA评分、APCHEⅡ评分、疾病转归呈正相关(P<0.05);Logistic回归分析显示,治疗3d后CD4^(+)/CD8^(+)比值≤1.10、PCT>19.18μg/L、CRP>122.98mg/L,治疗7d后CD4^(+)/CD8^(+)比值≤1.18、PCT>18.03μg/L、CRP>111.65mg/mL是SS患者病死的危险因素(P<0.05)。结论:CD4^(+)/CD8^(+)比值、PCT、CRP水平与SS患者疾病转归密切相关,检测其水平对临床预测患者疾病转归具有指导意义。展开更多
This paper deals with wave propagation and power coupling in blue-core helicon plasma driven by various antennas and frequencies.It is found that compared to non-blue-core mode,for blue-core mode,the wave can propagat...This paper deals with wave propagation and power coupling in blue-core helicon plasma driven by various antennas and frequencies.It is found that compared to non-blue-core mode,for blue-core mode,the wave can propagate in the core region,and it decays sharply outside the core.The power absorption is lower and steeper in radius for blue-core mode.Regarding the effects of antenna geometry for blue-core mode,it shows that half helix antenna yields the strongest wave field and power absorption,while loop antenna yields the lowest.Moreover,near axis,for antennas with m=+1,the wave field increases with axial distance.In the core region,the wave number approaches to a saturation value at much lower frequency for non-blue-core mode compared to blue-core mode.The total loading resistance is much lower for blue-core mode.These findings are valuable to understanding the physics of blue-core helicon discharge and optimizing the experimental performance of blue-core helicon plasma sources for applications such as space propulsion and material treatment.展开更多
文摘目的:探讨CD4^(+)/CD8^(+)比值降钙素原(Procallcitonin,PCT)、C反应蛋白(C-reactiveprotein,CRP)水平变化与感染性休克(Septicshock,SS)患者疾病转归的相关性。方法:选取我院2020年4月-2022年2月收治的135例SS患者为研究对象,根据患者28d疾病转归分为生存组(91例)和病死组(44例)。比较两组一般临床资料,比较两组治疗前、治疗3d、7d后CD4^(+)/CD8^(+)比值、PCT、CRP水平,分析治疗3d、7d后CD4^(+)/CD8^(+)比值、PCT、CRP水平与急性生理与慢性健康评估(Acute physiology and chronic health evaluationⅡ,APCHEⅡ)评分、序贯器官衰竭(Sepsis-related organ failure assessment,SOFA)评分及疾病转归的相关性,偏回归分析影响SS患者疾病转归的危险因素。结果:病死组年龄、治疗3d后、7d后APACHEⅡ评分、SOFA评分较生存组高(P<0.05);病死组治疗3d、7d后CD4^(+)/CD8^(+)比值低于生存组,PCT、CRP水平高于生存组(P<0.05);治疗3d、7d后,CD4+/CD8+比值与SOFA评分、APCHEⅡ评分、疾病转归呈负相关,PCT、CRP水平与SOFA评分、APCHEⅡ评分、疾病转归呈正相关(P<0.05);Logistic回归分析显示,治疗3d后CD4^(+)/CD8^(+)比值≤1.10、PCT>19.18μg/L、CRP>122.98mg/L,治疗7d后CD4^(+)/CD8^(+)比值≤1.18、PCT>18.03μg/L、CRP>111.65mg/mL是SS患者病死的危险因素(P<0.05)。结论:CD4^(+)/CD8^(+)比值、PCT、CRP水平与SS患者疾病转归密切相关,检测其水平对临床预测患者疾病转归具有指导意义。
基金Project supported by the National Natural Science Foundation of China(Grant No.92271113)the Fundamental Research Funds for the Central Universities(Grant No.2022CDJQY-003)+1 种基金Chongqing Entrepreneurship and Innovation Support Program for Overseas Returnees(Grant No.CX2022004)the Fund from Shanghai Engineering Research Center of Space Engine(Grant No.17DZ2280800).
文摘This paper deals with wave propagation and power coupling in blue-core helicon plasma driven by various antennas and frequencies.It is found that compared to non-blue-core mode,for blue-core mode,the wave can propagate in the core region,and it decays sharply outside the core.The power absorption is lower and steeper in radius for blue-core mode.Regarding the effects of antenna geometry for blue-core mode,it shows that half helix antenna yields the strongest wave field and power absorption,while loop antenna yields the lowest.Moreover,near axis,for antennas with m=+1,the wave field increases with axial distance.In the core region,the wave number approaches to a saturation value at much lower frequency for non-blue-core mode compared to blue-core mode.The total loading resistance is much lower for blue-core mode.These findings are valuable to understanding the physics of blue-core helicon discharge and optimizing the experimental performance of blue-core helicon plasma sources for applications such as space propulsion and material treatment.
