目的探讨头针联合吞咽功能康复训练治疗中风后假性球麻痹吞咽障碍患者的临床疗效。方法选取2023年1月—2023年12月期间保定市第一中心医院收治的中风后假性球麻痹吞咽障碍患者80例,按照随机对照试验设计方法分为对照组和观察组,每组各4...目的探讨头针联合吞咽功能康复训练治疗中风后假性球麻痹吞咽障碍患者的临床疗效。方法选取2023年1月—2023年12月期间保定市第一中心医院收治的中风后假性球麻痹吞咽障碍患者80例,按照随机对照试验设计方法分为对照组和观察组,每组各40例。对照组接受康复训练等常规西医治疗,观察组在对照组基础上联合头针治疗。治疗4周后,观察比较两组患者治疗前后中医证候积分、洼田氏饮水试验评分、Barthel指数评分、美国国立卫生研究院卒中量表(National institute of health stroke scale,NIHSS)评分、吞咽功能评估表(Standardized swallowing assessment,SSA)评分、吞咽障碍特异性生活质量量表(Swallowing quality of life,SWAL-QOL)评分改善状况,并比较两组患者临床总有效率和不良反应发生率。结果治疗后两组患者中医证候积分和洼田氏饮水试验评分均较治疗前降低,差异有统计学意义(P<0.05);且观察组中医证候积分和洼田氏饮水试验评分均低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者Barthel指数评分较治疗前升高,NIHSS评分较治疗前降低,差异有统计学意义(P<0.05);且观察组Barthel指数评分高于对照组,NIHSS评分低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者SSA评分较治疗前降低,SWAL-QOL评分较治疗前升高,差异有统计学意义(P<0.05);且观察组SSA评分低于对照组,SWAL-QOL评分高于对照组,差异有统计学意义(P<0.05)。治疗后观察组临床总有效率92.50%(37/40)高于对照组75.00%(30/40),差异有统计学意义(P<0.05)。治疗期间,两组患者均未出现晕针、血肿等不良反应发生情况。结论头针联合吞咽功能康复训练能改善中风后假性球麻痹吞咽障碍患者的神经损伤程度和吞咽功能,缓解患者临床症状表现,提高吞咽障碍患者生活质量,具有显著的临床疗效。展开更多
The alteration in surface color of metallic glasses(MGs)holds great significance in the context of microstructuredesign and commercial utility.It is essential to accurately describe the structures that are formed duri...The alteration in surface color of metallic glasses(MGs)holds great significance in the context of microstructuredesign and commercial utility.It is essential to accurately describe the structures that are formed during the laser and colorseparation processes in order to develop practical laser coloring applications.Due to the high oxidation sensitivity of Labasedmetallic glass,it can broaden the color range but make it more complex.Structure coloring by laser processing on thesurface of La-based metallic glass can be conducted after thermoplastic forming.It is particularly important to clarify therole of structure and composition in the surface coloring process.The aim is to study the relationship between amorphoussurface structural color,surface geometry,and oxide formation by laser processing in metallic glasses.The findings revealedthat the periodic structure primarily determines the surface color at laser energy densities below 1.0 J/mm^(2).In contrast,thesurface color predominantly depends on the proportion of oxides that are formed when energy densities exceed 1.0 J/mm^(2).Consequently,this study provides a novel concept for the fundamental investigation of laser coloring and establishes a newavenue for practical application.展开更多
文摘目的探讨头针联合吞咽功能康复训练治疗中风后假性球麻痹吞咽障碍患者的临床疗效。方法选取2023年1月—2023年12月期间保定市第一中心医院收治的中风后假性球麻痹吞咽障碍患者80例,按照随机对照试验设计方法分为对照组和观察组,每组各40例。对照组接受康复训练等常规西医治疗,观察组在对照组基础上联合头针治疗。治疗4周后,观察比较两组患者治疗前后中医证候积分、洼田氏饮水试验评分、Barthel指数评分、美国国立卫生研究院卒中量表(National institute of health stroke scale,NIHSS)评分、吞咽功能评估表(Standardized swallowing assessment,SSA)评分、吞咽障碍特异性生活质量量表(Swallowing quality of life,SWAL-QOL)评分改善状况,并比较两组患者临床总有效率和不良反应发生率。结果治疗后两组患者中医证候积分和洼田氏饮水试验评分均较治疗前降低,差异有统计学意义(P<0.05);且观察组中医证候积分和洼田氏饮水试验评分均低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者Barthel指数评分较治疗前升高,NIHSS评分较治疗前降低,差异有统计学意义(P<0.05);且观察组Barthel指数评分高于对照组,NIHSS评分低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者SSA评分较治疗前降低,SWAL-QOL评分较治疗前升高,差异有统计学意义(P<0.05);且观察组SSA评分低于对照组,SWAL-QOL评分高于对照组,差异有统计学意义(P<0.05)。治疗后观察组临床总有效率92.50%(37/40)高于对照组75.00%(30/40),差异有统计学意义(P<0.05)。治疗期间,两组患者均未出现晕针、血肿等不良反应发生情况。结论头针联合吞咽功能康复训练能改善中风后假性球麻痹吞咽障碍患者的神经损伤程度和吞咽功能,缓解患者临床症状表现,提高吞咽障碍患者生活质量,具有显著的临床疗效。
基金supported by the National Natural Science Foundation of China(Grant Nos.52071222 and 52471180)Guangdong Major Project of Basic and Applied Basic Research,China(Grant No.2019B030302010)+2 种基金Guangdong Basic and Applied Basic Research,China(Grant No.2020B1515130007)the National Key Research and Development Program of China(Grant No.2021YFA0716302)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB30000000).
文摘The alteration in surface color of metallic glasses(MGs)holds great significance in the context of microstructuredesign and commercial utility.It is essential to accurately describe the structures that are formed during the laser and colorseparation processes in order to develop practical laser coloring applications.Due to the high oxidation sensitivity of Labasedmetallic glass,it can broaden the color range but make it more complex.Structure coloring by laser processing on thesurface of La-based metallic glass can be conducted after thermoplastic forming.It is particularly important to clarify therole of structure and composition in the surface coloring process.The aim is to study the relationship between amorphoussurface structural color,surface geometry,and oxide formation by laser processing in metallic glasses.The findings revealedthat the periodic structure primarily determines the surface color at laser energy densities below 1.0 J/mm^(2).In contrast,thesurface color predominantly depends on the proportion of oxides that are formed when energy densities exceed 1.0 J/mm^(2).Consequently,this study provides a novel concept for the fundamental investigation of laser coloring and establishes a newavenue for practical application.
