To evaluate the clinical signification of coagulation factors(Ⅱ Ⅴ Ⅶ Ⅷ Ⅸ Ⅹ),Fibrinogen(Fib),PT and APTT in patients with hepatit is and cirrhosis.Method: 108 patients′ plasmas and 30 plasmas from normal subjec t...To evaluate the clinical signification of coagulation factors(Ⅱ Ⅴ Ⅶ Ⅷ Ⅸ Ⅹ),Fibrinogen(Fib),PT and APTT in patients with hepatit is and cirrhosis.Method: 108 patients′ plasmas and 30 plasmas from normal subjec ts were determined.Results: The lengthed PT and APTT were found in samples from 80. 56% and 71.30% patients with hepatitis and cirrhosis.Plasmas levels of Fib incre ased in patients with acute hepatitis,remained normal in patients with chronic p ersistent hepatitis,but decreased significantly in patients with chronic active hepatitis,cirrhosis and severe hepatitis( P< 0.05 ).The activity of coagula tion factors Ⅱ Ⅴ Ⅶ Ⅸ Ⅹ were lower than that in control group( P<0.05～0.001 ) ;but the activity of coagulation factor Ⅷ was higher than that in control group ( P<0.01 ).Conclusion: The studies indicated that the quantitative determin ation of coagulation activity had diagnostic and prognositc value in hepatitis a nd cirrhosis.展开更多
文摘To evaluate the clinical signification of coagulation factors(Ⅱ Ⅴ Ⅶ Ⅷ Ⅸ Ⅹ),Fibrinogen(Fib),PT and APTT in patients with hepatit is and cirrhosis.Method: 108 patients′ plasmas and 30 plasmas from normal subjec ts were determined.Results: The lengthed PT and APTT were found in samples from 80. 56% and 71.30% patients with hepatitis and cirrhosis.Plasmas levels of Fib incre ased in patients with acute hepatitis,remained normal in patients with chronic p ersistent hepatitis,but decreased significantly in patients with chronic active hepatitis,cirrhosis and severe hepatitis( P< 0.05 ).The activity of coagula tion factors Ⅱ Ⅴ Ⅶ Ⅸ Ⅹ were lower than that in control group( P<0.05～0.001 ) ;but the activity of coagulation factor Ⅷ was higher than that in control group ( P<0.01 ).Conclusion: The studies indicated that the quantitative determin ation of coagulation activity had diagnostic and prognositc value in hepatitis a nd cirrhosis.
