Twelve goats were divided into two study groups.Groupwas treated as control and groupwere fed sodium fluoride(NaF) orally according to their bodyweight. After 12 months of fluoride dosing, goats of group showed clinic...Twelve goats were divided into two study groups.Groupwas treated as control and groupwere fed sodium fluoride(NaF) orally according to their bodyweight. After 12 months of fluoride dosing, goats of group showed clinical signs of fluorosis .Erthrocyte were collected for analyses. The results showed that erthrocyte anti-oxidant function,ion pump function(ATPase),the contents of sialic acid(SA) and erythrocyte immune function were decreased due to excessive fluoride ingestion. A great number of erthrocyte deformed with polyhedral angel shape and star shape by the observation of scaning electronic microscope in group. The results provide the valuable clue of the anemia mechanism in chronic fluorosis.展开更多
文摘Twelve goats were divided into two study groups.Groupwas treated as control and groupwere fed sodium fluoride(NaF) orally according to their bodyweight. After 12 months of fluoride dosing, goats of group showed clinical signs of fluorosis .Erthrocyte were collected for analyses. The results showed that erthrocyte anti-oxidant function,ion pump function(ATPase),the contents of sialic acid(SA) and erythrocyte immune function were decreased due to excessive fluoride ingestion. A great number of erthrocyte deformed with polyhedral angel shape and star shape by the observation of scaning electronic microscope in group. The results provide the valuable clue of the anemia mechanism in chronic fluorosis.