【目的】分析不同分类、分级胃神经内分泌肿瘤(G-NEN)患者的临床病理特征及预后。【方法】回顾性分析2016年6月至2022年1月盐城市第三人民医院收治的64例G-NEN患者,根据2019第五版WHO消化系统肿瘤分类标准对其进行病理分类及分级,对患...【目的】分析不同分类、分级胃神经内分泌肿瘤(G-NEN)患者的临床病理特征及预后。【方法】回顾性分析2016年6月至2022年1月盐城市第三人民医院收治的64例G-NEN患者,根据2019第五版WHO消化系统肿瘤分类标准对其进行病理分类及分级,对患者临床资料、病理学特点、免疫表型、治疗及预后情况进行分析。【结果】64例G-NEN患者男性多于女性,平均年龄为(65.7±9.01)岁,患者多数表现为腹痛。低级别G-NEN主要位于胃体,高级别G-NEN及混合性神经内分泌-非神经内分泌肿瘤(MiNEN)以贲门多见。不同病理类型患者年龄、肿瘤最大径、肿瘤部位、肿瘤数目、胃镜下形态、淋巴结转移情况、TNM分期比较,差异有统计学意义(P<0.05)。免疫组化突触素(Syn)的表达明显高于嗜铬素(CgA),差异具有统计学意义(P<0.05)。随访5~60个月,低级别G-NEN预后优于高级别G-NEN、MiNEN组患者(P<0.05),NET G 3与NEC、NEC与MiNEN预后比较,差异无统计学意义(P>0.05)。【结论】G-NEN以老年男性多见,主要表现为腹痛,不同病理类型G-NEN具有不同的临床病理特点及生物学行为,高级别G-NEN与MiNEN患者预后较差。展开更多
This paper reviewed the concept,formation and function of gap and developed a new concept,canopy rift.It refers to the small 1-25m 2 rift in the canopy caused by the different distribution pattern of the canopy specie...This paper reviewed the concept,formation and function of gap and developed a new concept,canopy rift.It refers to the small 1-25m 2 rift in the canopy caused by the different distribution pattern of the canopy species or breakage,standing death and treefall.Canopy gap,mainly caused by small scale disturbances including natural disturbance regime and human disturbance regime,is an important phase in the forest regeneration cycle.It plays a leading role in the formation and maintenance of the patches mosaic structure in a forest community.Corresponding to the three phases of the forest regeneration cycle,patches can be classified into three types:gap phase,building phase and mature forest.Many factors may contribute to the maintenance of biodiversity.Here we divided them into ① intrinsic factors,mainly including the biological and ecological characteristics of the species and ② external factors,the heterogeneity of habitat.The formation of gaps leads to the diversification of micro environment,and changes the type and magnitude of understory.Gap impacts the forest micro environment,community structure and dynamic process.Gap causes different status of renewal between pioneer species and climax species,and generates the patch which is the different in the constitute of woods,population dynamic and growing speed.It leads to the diversity of community difference and species component,which is the difference of species between community patches.Gap is of great significance in enhancing and maintaining species diversity for it may enhance habitat heterogeneity.展开更多
文摘【目的】分析不同分类、分级胃神经内分泌肿瘤(G-NEN)患者的临床病理特征及预后。【方法】回顾性分析2016年6月至2022年1月盐城市第三人民医院收治的64例G-NEN患者,根据2019第五版WHO消化系统肿瘤分类标准对其进行病理分类及分级,对患者临床资料、病理学特点、免疫表型、治疗及预后情况进行分析。【结果】64例G-NEN患者男性多于女性,平均年龄为(65.7±9.01)岁,患者多数表现为腹痛。低级别G-NEN主要位于胃体,高级别G-NEN及混合性神经内分泌-非神经内分泌肿瘤(MiNEN)以贲门多见。不同病理类型患者年龄、肿瘤最大径、肿瘤部位、肿瘤数目、胃镜下形态、淋巴结转移情况、TNM分期比较,差异有统计学意义(P<0.05)。免疫组化突触素(Syn)的表达明显高于嗜铬素(CgA),差异具有统计学意义(P<0.05)。随访5~60个月,低级别G-NEN预后优于高级别G-NEN、MiNEN组患者(P<0.05),NET G 3与NEC、NEC与MiNEN预后比较,差异无统计学意义(P>0.05)。【结论】G-NEN以老年男性多见,主要表现为腹痛,不同病理类型G-NEN具有不同的临床病理特点及生物学行为,高级别G-NEN与MiNEN患者预后较差。
文摘This paper reviewed the concept,formation and function of gap and developed a new concept,canopy rift.It refers to the small 1-25m 2 rift in the canopy caused by the different distribution pattern of the canopy species or breakage,standing death and treefall.Canopy gap,mainly caused by small scale disturbances including natural disturbance regime and human disturbance regime,is an important phase in the forest regeneration cycle.It plays a leading role in the formation and maintenance of the patches mosaic structure in a forest community.Corresponding to the three phases of the forest regeneration cycle,patches can be classified into three types:gap phase,building phase and mature forest.Many factors may contribute to the maintenance of biodiversity.Here we divided them into ① intrinsic factors,mainly including the biological and ecological characteristics of the species and ② external factors,the heterogeneity of habitat.The formation of gaps leads to the diversification of micro environment,and changes the type and magnitude of understory.Gap impacts the forest micro environment,community structure and dynamic process.Gap causes different status of renewal between pioneer species and climax species,and generates the patch which is the different in the constitute of woods,population dynamic and growing speed.It leads to the diversity of community difference and species component,which is the difference of species between community patches.Gap is of great significance in enhancing and maintaining species diversity for it may enhance habitat heterogeneity.
