To explore the inhibiting tumor effect of D.denneanum in vivo.The tumor S180 loading mouse model was established.Investigated the antitumor activity of D.denneanum by observing the tumor、spleen and thymus weight of t...To explore the inhibiting tumor effect of D.denneanum in vivo.The tumor S180 loading mouse model was established.Investigated the antitumor activity of D.denneanum by observing the tumor、spleen and thymus weight of these mice after administrating the drug for 10 days.Results: The ratio of inhibiting tumor of polysaccharides are over 50%,the ratio of inhibiting tumor of ethanol extracts are 64.81%,57.26%.Compared with the positive group,the index of spleen and the index of thymus of polysaccharides have obviously rise.Conclusion: The polysaccharides of D.denneanum can inhibiting tumor and advance immunity of mouse bearing tumor.The ethanol extracts of D.denneanum can inhibiting tumor too,and can advance immunity of mouse bearing tumor in some degree.展开更多
[目的]采用超声波技术辅助提取黄柏多糖。[方法]通过正交设计对提取工艺进行优化,考察因素为提取温度、提取时间、pH值和次数。[结果]影响黄柏多糖提取的主要因素是提取次数,优选方案为温度95℃、时间25 m in、pH 9、提取3次。[结论]该...[目的]采用超声波技术辅助提取黄柏多糖。[方法]通过正交设计对提取工艺进行优化,考察因素为提取温度、提取时间、pH值和次数。[结果]影响黄柏多糖提取的主要因素是提取次数,优选方案为温度95℃、时间25 m in、pH 9、提取3次。[结论]该方法简单、高效,具有良好的精密度和稳定性,重现性好,是提取黄柏多糖的一个可行的方法。展开更多
The experiment combine high throughput preparation technology with the new drug finding of Ⅱ diabetes mellitus, through making use of modern separation and purification technology prepared for the natural product lib...The experiment combine high throughput preparation technology with the new drug finding of Ⅱ diabetes mellitus, through making use of modern separation and purification technology prepared for the natural product library of Ⅱ diabetes mellitus. The library offered more and more comprehensive compound to drug screening, and made the drug screening of Ⅱ diabetes mellitus realize high throughput, also it broke a new path for the therapy of Ⅱ diabetes mellitus.展开更多
文摘To explore the inhibiting tumor effect of D.denneanum in vivo.The tumor S180 loading mouse model was established.Investigated the antitumor activity of D.denneanum by observing the tumor、spleen and thymus weight of these mice after administrating the drug for 10 days.Results: The ratio of inhibiting tumor of polysaccharides are over 50%,the ratio of inhibiting tumor of ethanol extracts are 64.81%,57.26%.Compared with the positive group,the index of spleen and the index of thymus of polysaccharides have obviously rise.Conclusion: The polysaccharides of D.denneanum can inhibiting tumor and advance immunity of mouse bearing tumor.The ethanol extracts of D.denneanum can inhibiting tumor too,and can advance immunity of mouse bearing tumor in some degree.
文摘[目的]采用超声波技术辅助提取黄柏多糖。[方法]通过正交设计对提取工艺进行优化,考察因素为提取温度、提取时间、pH值和次数。[结果]影响黄柏多糖提取的主要因素是提取次数,优选方案为温度95℃、时间25 m in、pH 9、提取3次。[结论]该方法简单、高效,具有良好的精密度和稳定性,重现性好,是提取黄柏多糖的一个可行的方法。
文摘The experiment combine high throughput preparation technology with the new drug finding of Ⅱ diabetes mellitus, through making use of modern separation and purification technology prepared for the natural product library of Ⅱ diabetes mellitus. The library offered more and more comprehensive compound to drug screening, and made the drug screening of Ⅱ diabetes mellitus realize high throughput, also it broke a new path for the therapy of Ⅱ diabetes mellitus.
