基金Supported by Grants from Program for New Century Excellent Talents in University(No.NCET-05-0745)National Natural Science Foundation of China(No.30500450)+2 种基金Natural Science Foundation of Guangdong Province(No.8151063201000047)the 211 grant of Ministry of Education of China(MOE)the Key Discipline of Biochemistry and Molecular Biology of Guangdong Province.