Tendon tissue engineering is one of the research fields with longhistory, which has achieved dramatic advances This paper reviewed some recent original articles, mainly in sources of seeding cells of tendon tissue eng...Tendon tissue engineering is one of the research fields with longhistory, which has achieved dramatic advances This paper reviewed some recent original articles, mainly in sources of seeding cells of tendon tissue engineering, the level of immunological reaction with allogeneic tendon cells, preparation and screening of scaffold materials with specific mechanical and degenerating properties, the interaction of cells, scaffold materials, and so on To establish the standard tendon cell line for research has significance in the study of the biological characteristics of tendon cells, the cell model for immortalization, and screening the various scaffold materials The immunological reaction of the tissue engineered tendon with allogeneic cells in the research and future clinical applications must be clarified It is requested by tissue engineering research that the scaffold materials with specific mechanical and degenerating properties and the three dimensional culture technique mimic microenviroment in vivo, including the mechnical stress and strain All of those should be extensivly studied to lay a solid foundation for ultimate clinical展开更多
文摘Tendon tissue engineering is one of the research fields with longhistory, which has achieved dramatic advances This paper reviewed some recent original articles, mainly in sources of seeding cells of tendon tissue engineering, the level of immunological reaction with allogeneic tendon cells, preparation and screening of scaffold materials with specific mechanical and degenerating properties, the interaction of cells, scaffold materials, and so on To establish the standard tendon cell line for research has significance in the study of the biological characteristics of tendon cells, the cell model for immortalization, and screening the various scaffold materials The immunological reaction of the tissue engineered tendon with allogeneic cells in the research and future clinical applications must be clarified It is requested by tissue engineering research that the scaffold materials with specific mechanical and degenerating properties and the three dimensional culture technique mimic microenviroment in vivo, including the mechnical stress and strain All of those should be extensivly studied to lay a solid foundation for ultimate clinical
