[Objective]To predict prevalence of fleas via a simple epidemiological model.[Method]The field investigation was carried out in 23 locations in Yunnan Province.A simple epidemiological model was involved mean abundanc...[Objective]To predict prevalence of fleas via a simple epidemiological model.[Method]The field investigation was carried out in 23 locations in Yunnan Province.A simple epidemiological model was involved mean abundance and variance of abundance.[Result]The prevalence of fleas increased with their mean abundance in logistic curve.A linear correlation of the predicted prevalence against observed prevalence did not differ significantly from unity.[Conclusion]Prevalence could be explained simply by their mean abundance.展开更多
目的探讨脂肪酸结合蛋白5(fatty acid binding protein 5,FABP5)在宫颈癌组织的表达及其与临床预后的关系.方法行广泛性子宫切除术和系统性腹膜后淋巴结切除术的早期宫颈癌组织蜡块共206例(淋巴结转移阳性41例,阴性165例),另选取相匹配...目的探讨脂肪酸结合蛋白5(fatty acid binding protein 5,FABP5)在宫颈癌组织的表达及其与临床预后的关系.方法行广泛性子宫切除术和系统性腹膜后淋巴结切除术的早期宫颈癌组织蜡块共206例(淋巴结转移阳性41例,阴性165例),另选取相匹配年龄的40例因子宫肌瘤行全子宫切除的正常宫颈组织作为空白对照组.采用免疫组化法检测FABP5在206例早期宫颈癌组织标本及正常宫颈组织中的表达;分析FABP5与宫颈癌患者临床、病理参数之间的相关性;采用多变量COX比例风险模型评估FABP5在宫颈癌预后中的价值.结果FABP5高表达主要集中在细胞核和细胞浆中;宫颈癌组织中FABP5的表达较正常宫颈组织显著升高(P<0.05);且在淋巴结转移阳性组较阴性组表达显著升高(P<0.05).而在正常宫颈组织中,FABP5仅在宫颈上皮层低表达;FABP5与FIGO分期(P<0.001)、肿瘤大小(P=0.011)、淋巴结转移(P<0.001)和淋巴脉管浸润(P<0.001)显著相关.多变量COX比例风险模型分析结果显示年龄、盆腔淋巴结转移、肿瘤大小和FABP5为宫颈癌的独立预后因素.生存分析显示FABP5高表达与不良预后显著相关(P<0.05).结论FABP5在宫颈癌中高表达,且可作为宫颈癌不良预后的预测指标.展开更多
基金Supported by Yunnan Provincial Foundation for Key Scientific Projects (2007C0005Z2)~~
文摘[Objective]To predict prevalence of fleas via a simple epidemiological model.[Method]The field investigation was carried out in 23 locations in Yunnan Province.A simple epidemiological model was involved mean abundance and variance of abundance.[Result]The prevalence of fleas increased with their mean abundance in logistic curve.A linear correlation of the predicted prevalence against observed prevalence did not differ significantly from unity.[Conclusion]Prevalence could be explained simply by their mean abundance.
文摘目的探讨脂肪酸结合蛋白5(fatty acid binding protein 5,FABP5)在宫颈癌组织的表达及其与临床预后的关系.方法行广泛性子宫切除术和系统性腹膜后淋巴结切除术的早期宫颈癌组织蜡块共206例(淋巴结转移阳性41例,阴性165例),另选取相匹配年龄的40例因子宫肌瘤行全子宫切除的正常宫颈组织作为空白对照组.采用免疫组化法检测FABP5在206例早期宫颈癌组织标本及正常宫颈组织中的表达;分析FABP5与宫颈癌患者临床、病理参数之间的相关性;采用多变量COX比例风险模型评估FABP5在宫颈癌预后中的价值.结果FABP5高表达主要集中在细胞核和细胞浆中;宫颈癌组织中FABP5的表达较正常宫颈组织显著升高(P<0.05);且在淋巴结转移阳性组较阴性组表达显著升高(P<0.05).而在正常宫颈组织中,FABP5仅在宫颈上皮层低表达;FABP5与FIGO分期(P<0.001)、肿瘤大小(P=0.011)、淋巴结转移(P<0.001)和淋巴脉管浸润(P<0.001)显著相关.多变量COX比例风险模型分析结果显示年龄、盆腔淋巴结转移、肿瘤大小和FABP5为宫颈癌的独立预后因素.生存分析显示FABP5高表达与不良预后显著相关(P<0.05).结论FABP5在宫颈癌中高表达,且可作为宫颈癌不良预后的预测指标.
