下肢静脉曲张(VVLE)是临床常见病,我国成年人中约占10%~25%,其中女性发病率稍高,但其发病机制尚未明确。患者可出现下肢肿胀、皮肤瘙痒、色素沉着、血栓性浅静脉炎、皮肤溃疡、下肢深静脉血栓(LDVT)等。手术是治疗下肢静脉曲张最有效的...下肢静脉曲张(VVLE)是临床常见病,我国成年人中约占10%~25%,其中女性发病率稍高,但其发病机制尚未明确。患者可出现下肢肿胀、皮肤瘙痒、色素沉着、血栓性浅静脉炎、皮肤溃疡、下肢深静脉血栓(LDVT)等。手术是治疗下肢静脉曲张最有效的方法,血管内热消融术以其创伤小、出血少、恢复快,效果好等优势,在临床上已逐步成为临床治疗的主要手段。但该方法易导致静脉腔内热诱导血栓形成(EHIT),影响患者的康复。目前,国外对EHIT的防治缺乏指导意见,且常用抗凝药物存在出血风险或不便等问题,探索更加安全有效的预防和治疗措施成为医学界的研究热点。近年来,中医药因其具有改善病人整体状况、提高免疫功能、促进康复等作用而备受重视。本文就其病因病机及治疗新进展进行综述,为此病的防治提供参考。Lower extremity varicose veins (VVLE) is a common clinical disease, accounting for 10%~25% of adults in China, of which the female incidence rate is slightly higher, but its pathogenesis has not yet been clarified. Patients may experience lower limb swelling, skin itching, pigmentation, thrombotic superficial phlebitis, skin ulcers, and lower limb deep vein thrombosis (LDVT). Surgery is the most effective method for treating lower limb varicose veins, and intravascular thermal ablation has gradually become the main clinical treatment method due to its advantages of minimal trauma, less bleeding, fast recovery, and good results. But, this method can easily lead to heat induced thrombosis (EHIT) in the venous lumen, affecting the patient’s recovery. At present, there is a lack of guidance on the prevention and treatment of EHIT in foreign countries, and commonly used anticoagulant drugs have problems such as bleeding risk or inconvenience. Exploring safer and more effective prevention and treatment measures has become a research hotspot in the medical community. In recent years, traditional Chinese medicine has been highly valued for its ability to improve the overall condition of patients, enhance immune function, and promote rehabilitation. This article reviews the etiology, pathogenesis, and new advances in treatment of this disease, providing reference for its prevention and treatment.展开更多
随着经济的飞速发展,人们的生活习惯也发生了改变,人们习惯于静坐、高热量、高脂食物等,体重超标的人群越来越多,糖尿病发病率也随之升高。糖尿病是一种以高血糖为主要表现的代谢疾病,其主要表现为胰岛素分泌降低或出现胰岛素抵抗,从而...随着经济的飞速发展,人们的生活习惯也发生了改变,人们习惯于静坐、高热量、高脂食物等,体重超标的人群越来越多,糖尿病发病率也随之升高。糖尿病是一种以高血糖为主要表现的代谢疾病,其主要表现为胰岛素分泌降低或出现胰岛素抵抗,从而导致一系列的代谢综合征。根据国际糖尿病联合会的资料,目前全世界有5.37亿人罹患糖尿病,这一数字在过去五年中以1.2%的速度增长,大约占世界人口的10%。预计到2045年,患糖尿病的人将达到7.83亿人。然而,中国18岁及以上的糖尿病(WHO)发病率高达11.2%。一些糖尿病病人由于长期低血糖,在糖毒性作用下,外周神经受损,下肢微循环受损,从而形成了糖尿病足(DF)。糖尿病引起的并发症使其死亡率上升,严重者可出现失明、截肢和其他心脑血管疾病。可采用相应的药物来控制血糖,其次要妥善进行清创等抗感染治疗。现对此病的中西医结合治疗综述如下。With the rapid development of the economy, people’s living habits have also changed. People are accustomed to sitting still, high calories, high-fat food, etc. More and more people are overweight, and the incidence rate of diabetes has also increased. Diabetes is a metabolic disease with hyperglycemia as its main manifestation. Its main manifestation is the reduction of insulin secretion or insulin resistance, which leads to a series of metabolic syndrome. According to the International diabetes Federation, 537 million people in the world are suffering from diabetes at present, which has increased by 1.2% in the past five years, accounting for about 10% of the world’s population. It is estimated that 783 million people will suffer from diabetes by 2045. However, the incidence rate of diabetes (WHO) in China aged 18 years and over is as high as 11.2%. Some patients with diabetes suffer from long-term hypoglycemia. Under the effect of glucose toxicity, peripheral nerves and microcirculation of lower limbs are damaged, thus forming diabetes foot (DF). Complications caused by diabetes make the mortality rate rise. In serious cases, blindness, amputation and other cardiovascular and cerebrovascular diseases may occur. Corresponding drugs can be used to control blood sugar, and secondly, appropriate anti-infective treatments such as debridement should be carried out. The summary of the integrated treatment of this disease with traditional Chinese and Western medicine is as follows.展开更多
文摘下肢静脉曲张(VVLE)是临床常见病,我国成年人中约占10%~25%,其中女性发病率稍高,但其发病机制尚未明确。患者可出现下肢肿胀、皮肤瘙痒、色素沉着、血栓性浅静脉炎、皮肤溃疡、下肢深静脉血栓(LDVT)等。手术是治疗下肢静脉曲张最有效的方法,血管内热消融术以其创伤小、出血少、恢复快,效果好等优势,在临床上已逐步成为临床治疗的主要手段。但该方法易导致静脉腔内热诱导血栓形成(EHIT),影响患者的康复。目前,国外对EHIT的防治缺乏指导意见,且常用抗凝药物存在出血风险或不便等问题,探索更加安全有效的预防和治疗措施成为医学界的研究热点。近年来,中医药因其具有改善病人整体状况、提高免疫功能、促进康复等作用而备受重视。本文就其病因病机及治疗新进展进行综述,为此病的防治提供参考。Lower extremity varicose veins (VVLE) is a common clinical disease, accounting for 10%~25% of adults in China, of which the female incidence rate is slightly higher, but its pathogenesis has not yet been clarified. Patients may experience lower limb swelling, skin itching, pigmentation, thrombotic superficial phlebitis, skin ulcers, and lower limb deep vein thrombosis (LDVT). Surgery is the most effective method for treating lower limb varicose veins, and intravascular thermal ablation has gradually become the main clinical treatment method due to its advantages of minimal trauma, less bleeding, fast recovery, and good results. But, this method can easily lead to heat induced thrombosis (EHIT) in the venous lumen, affecting the patient’s recovery. At present, there is a lack of guidance on the prevention and treatment of EHIT in foreign countries, and commonly used anticoagulant drugs have problems such as bleeding risk or inconvenience. Exploring safer and more effective prevention and treatment measures has become a research hotspot in the medical community. In recent years, traditional Chinese medicine has been highly valued for its ability to improve the overall condition of patients, enhance immune function, and promote rehabilitation. This article reviews the etiology, pathogenesis, and new advances in treatment of this disease, providing reference for its prevention and treatment.
文摘随着经济的飞速发展,人们的生活习惯也发生了改变,人们习惯于静坐、高热量、高脂食物等,体重超标的人群越来越多,糖尿病发病率也随之升高。糖尿病是一种以高血糖为主要表现的代谢疾病,其主要表现为胰岛素分泌降低或出现胰岛素抵抗,从而导致一系列的代谢综合征。根据国际糖尿病联合会的资料,目前全世界有5.37亿人罹患糖尿病,这一数字在过去五年中以1.2%的速度增长,大约占世界人口的10%。预计到2045年,患糖尿病的人将达到7.83亿人。然而,中国18岁及以上的糖尿病(WHO)发病率高达11.2%。一些糖尿病病人由于长期低血糖,在糖毒性作用下,外周神经受损,下肢微循环受损,从而形成了糖尿病足(DF)。糖尿病引起的并发症使其死亡率上升,严重者可出现失明、截肢和其他心脑血管疾病。可采用相应的药物来控制血糖,其次要妥善进行清创等抗感染治疗。现对此病的中西医结合治疗综述如下。With the rapid development of the economy, people’s living habits have also changed. People are accustomed to sitting still, high calories, high-fat food, etc. More and more people are overweight, and the incidence rate of diabetes has also increased. Diabetes is a metabolic disease with hyperglycemia as its main manifestation. Its main manifestation is the reduction of insulin secretion or insulin resistance, which leads to a series of metabolic syndrome. According to the International diabetes Federation, 537 million people in the world are suffering from diabetes at present, which has increased by 1.2% in the past five years, accounting for about 10% of the world’s population. It is estimated that 783 million people will suffer from diabetes by 2045. However, the incidence rate of diabetes (WHO) in China aged 18 years and over is as high as 11.2%. Some patients with diabetes suffer from long-term hypoglycemia. Under the effect of glucose toxicity, peripheral nerves and microcirculation of lower limbs are damaged, thus forming diabetes foot (DF). Complications caused by diabetes make the mortality rate rise. In serious cases, blindness, amputation and other cardiovascular and cerebrovascular diseases may occur. Corresponding drugs can be used to control blood sugar, and secondly, appropriate anti-infective treatments such as debridement should be carried out. The summary of the integrated treatment of this disease with traditional Chinese and Western medicine is as follows.
